Importance of the stem cell microenvironment for ophthalmological cell-based therapy. World J Stem Cells. 2015; 7: 448-460.Importance of the stem cell microenvironment for ophthalmological cell-based therapy[J]. Peng-Xia Wan,Bo-Wen Wang,Zhi-Chong Wang.World Journal of Stem Cells. 2015(02)Wan...
Here we review the applicability of multiple stem cell types for tissue engineering of cartilage, trachea, vocal folds and nerves for head and neck injuries. The ability of the cells to self-renew and maintain their pluripotency state makes them an attractive tool in tissue engineering. 展开 ...
progenitor cells (HSPCs) [33,34]. A work by Filion et al. showed that in human embryonic stem cells (HES) subjected to ionizing radiation the expression of this IAP along with checkpoint kinase 2 (Chk2) helps to recuperate DNA damage without the dependency on p21 to support cell cycle a...
One characteristic quality of stem cells is that they are immortal and can divide indefinitely. This, however, is a property that stem cells have only at their early undifferentiated stage. As stem cells continue to develop, mature and specialize into a particular type of cell, they lose this ...
Tumor heterogeneity can be traced back to a small subset of cancer stem cells (CSCs), which can be derived from a single stem cell and show chemoresistance. Recent studies showed that CSCs are sensitive to mitochondrial targeting antibiotics such as doxycycline. However, little is known about how...
Tumor heterogeneity can be traced back to a small subset of cancer stem cells (CSCs), which can be derived from a single stem cell and show chemoresistance. Recent studies showed that CSCs are sensitive to mitochondrial targeting antibiotics such as doxycycline. However, little is known about how...
The establishment of human embryonic stem cell lines dramatically impulses the studies on human stem cells, and accelerates the tempo of the application of stem cells in treating human diseases. However, many problems maintain unresolved before the clinical application of stem cells and a great amount...
These studies have provided a wealth of insight and have shown that cell geometry and size play an important role in organizing the cytoskeleton and in directing growth, death, and differentiation of mesenchymal stem cells (MSCs). However, 2D cell culture does not fully capture the cellular ...
Critical Appraisal of the Side Population Assay in Stem Cell and Cancer Stem Cell Research The "Side Population" (SP) discrimination assay is a flow cytometry method used to detect stem cells based on the dye efflux properties of ABC transporters... A Golebiewska,NHC Brons,R Bjerkvig,... ...
Chimerism testing after allogeneic stem cell transplantation: importance of timing and optimal technique for testing in different clinical-biological situations doi:10.1038/sj.leu.2402754STEM cellsCELL transplantationPOLYMERASE chain reactionCAPILLARY electrophoresisLeukemia (2003) 17, 220. doi...