Some thoughts on the importance of insulin in the regulation of the blood glucose level. Experientia 1996;52:421-5.Newsholme EA, Dimitriadis G: Some thoughts on the importance of insulin in the regulation of the blood glucose level. Experientia 52:421- 425, 1996...
Differential effects of cis and trans fatty acids on insulin release from isolated mouse islets Previously, it was demonstrated that the chain length and degree of unsaturation are of importance for the insulinotropic effect of fatty acids. However, ... KK Alstrup,S Gregersen,HM Jensen,... - ...
It has recently been suggested that skeletal muscle has an important role in insulin resistance in obesity, in addition to exercise tolerance and the fat index. The aim of this study was to identify body composition factors that contribute to improvement of insulin resistance in female patients wit...
in various circulating metabolites, insulin secretion and -sensitivity and energy expenditure in metabolically healthy adults. These rhythms have been shown to be disturbed in adults with obesity-related metabolic disturbances. Moreover, eating and being (in)active at a time that the body is not ...
H Hubert - 《Annual Review of Public Health》 被引量: 0发表: 1986年 Uric acid and coronary heart disease risk: evidence for a role of uric acid in the obesity-insulin resistance syndrome. The Normative Aging Study. Various epidemiologic studies have linked an increase in serum uric acid leve...
Update on therapeutic strategies to increase adiponectin function and secretion in metabolic syndrome Changes in diagnostic criteria have impacted on the definition of the metabolic syndrome. The central aetiological importance of insulin resistance has les... Montecucco,Mach - 《Diabetes Obesity & Metabol...
Ageing is associated with a variety of pathophysiological changes, including development of insulin resistance, progressive decline in -cell function and chronic inflammation, all of which affect metabolic homeostasis in response to nutritional and environmental stimuli. SIRT1, the mammalian nicotinamide aden...
Insulin resistance is the cornerstone of metabolic syndrome X, with secondary hyperinsulinism. Upper body obesity is associated with metabolic syndrome X. Simple waist measurements can detect the subjects (10-15% of the population) at increased CV risk with a sensitivity of 70%. This is ...
Explain the function of a chaperone protein. Explain why the insulin signal transduction pathway seems to play an important role in aging. Describe the effects of a shortage of cholesterol in the body. Explain why industrialized food production requires large inputs of energy. Why does it result...
Recent work from the University of Kentucky College of Medicine published in Trends in Endocrinology & Metabolism discusses an essential signaling pathway that causes metabolic dysfunction including insulin resistance and obesity.