Human genome research has made it possible to identify the presence of gene mutations in persons with specific genetic conditions, who may be carriers of genetic disorders, or who are at risk for future development of inherited diseases. Gene discovery has the potential to identify individual respon...
2014. The Impact of Genetic Steroid Disorders on Human Fertility. Genetic Steroid Disorders, 331-342. /David E. Reichman, Zev Rosenwaks. . The Impact of Genetic Steroid Disorders on Human Fertility. 2014:, 331-342. /David E.Reichman, ZevRosenwaks. The Impact of Genetic Steroid Disorders ...
KS Kendler - 《Journal of Psychiatric Research》 被引量: 203发表: 1987年 Familial Aggregation of Adolescent Personality Disorders A family study of DSM-III-R personality disorders was conducted in the families of 66 clinically referred adolescents to examine the validity of personalit... BA Johnso...
For the SCT group, recruitment bias was assessed; three subgroups were identified: (1) “Active prospective follow-up”, which included families who were actively followed after prenatal diagnosis (51% of the SCT group); (2) “Information seeking parents,” which included families who were ...
The mammalian gut is home to a diverse microbial ecosystem, whose composition affects various physiological traits of the host. Next-generation sequencing-based metagenomic approaches demonstrated how the interplay of host genetics, bacteria, and environ
The majority of genetic tests are used in diagnosis and/or genetic counseling for rare, single-gene disorders in a limited number of people. However, as more tests are being considered for newborn screening, and associations between genes and common diseases are being discovered, the impact of ...
METABOLIC disordersOVERWEIGHT childrenGENETIC polymorphismsEssential arterial hypertension is a multifactor pathology and in its realization genetic and environmental factors play a very important role. It is estimated that 30-60% of the variation of the arterial hypertension among people is due to ...
Individuals experiencing socioeconomic disadvantage in childhood have a higher rate of inflammation-related diseases decades later. Little is known about the mechanisms linking early life experiences to the functioning of the immune system in adulthood.
risk-taking, such that risk-taking is the combined function of adverse experiences in early years, low self-control, and carriage of sensitive genes. Practically, intervention strategies should reduce childhood adversities, build up self-control, and consider the potential impacts of genetic plasticity...
made in understanding the underlying pathophysiology for individually rare childhood dementia conditions, with a growing number of genetic causes still being discovered, scientific advancements have yet to translate into accessible healthcare services and psychosocial supports for affected families [11,17,18...