functional modulation of bone marrow (BM)–derived dendritic cells (DCs) rather thana direct effect on T cells. Under the influence of lead, the DCs preferentially polarize antigen-specific T cells toTh2 cellsin vitro and inhibit Th1 effects on humoral and cell-mediated immunity in vivo.148...
Background The ketogenic diet (KD) is effective to fight obesity and has therapeutic effects on various body systems. Aim/objectives This study aimed to evaluate the role of KD in improving immune response against cyclophosphamide (CTX)-induced immunosuppression in rats. Methods Youn...
Immunosuppression in juvenile carp,Cyprinus carpio L.:The effects of the corticosteroids triamcinolone acetonide and hydrocortisone 21-hemisuccinate (cortisol) on... G Houghton,RA Matthews - 《Journal of Fish Diseases》 被引量: 119发表: 1990年 Addition of inhaled corticosteroids to systemic immunosuppre...
2. HIV-induce immunosuppressive effects, which reduce the immune system's ability to eliminate HPV infections allowing it to remain in the body for long periods of time as a result of decreased immune surveillance. The weakened immunological milieu enhances HR-HPV integration into the host genome,...
2. HIV-induce immunosuppressive effects, which reduce the immune system's ability to eliminate HPV infections allowing it to remain in the body for long periods of time as a result of decreased immune surveillance. The weakened immunological milieu enhances HR-HPV integration into the host genome,...
This review summarizes current knowledge regarding immunosuppressive drug classes as well as their dosages and application regimens with consideration of species-specific drug metabolization and side effects. It also summarizes contemporary knowledge of novel immunomodulatory strategies, such as the use of ...
However, a retrospective study including 275 patients with COVID-19 found no beneficial effects for Tα1 on the recovery of CD4+ and CD8+ T cell counts and viral clearance during COVID-19 convalescence [111]. Another study including 771 critically ill COVID-19 patients also demonstrated ...
What biological effects does the release of renin have on the entire body? What is the mechanism of action for formaldehydes? For what organism(s) is the chemical effective? What can the metabolome tell us about a biological system? What are the main regulatory mechanisms that allow pH to ...
Based on synergistic effects between different immuno- suppressants,187 a combined approach using conventional agents such as CsA, MMF and prednisolone is recommended, especially for long-term immunosuppression.18,19 This also allows for the dose reduction of single immunosuppressants, ideally leading ...
8 Moreover, similar differentiation effects could be observed by chemotherapeutic agent treatment on in vitro-generated MDSCs.9 However, most evidence of therapeutic targeting of MDSCs in human comes from secondary observations in patients undergoing standard or experimental therapies.10 Therefore, ...