The prognosis model constructed using nine gene sets can effectively predict prognosis. Prognostic models were significantly associated with tumor mutational burden (TMB), tumor immune microenvironment (TIME), immune checkpoints, and somatic mutations. A composite nomogram was constr...
26], probably because of the highly conserved molecular patterns associated with immune-mediated tissue destruction. The first comparative analysis was performed by Morgun et al. [25] who, after identifying a gene set predictive of acute-rejection in a series of heart allograft...
Immunologic Constant of Rejection signature (ICR) is a 20-gene expression signature of cytotoxic immune response with prognostic value in some solid cancers. Our objective was to assess its predictive value for benefit from anti-PD1/PDL1 in patients with advanced NSCLC. Methods: We retrospectively ...
VH gene products allow specific communication among immunologic cell sets - Woodland, Cantor - 1980 () Citation Context ...ell-mediated circuits (1-5). Networks related by complementary idiotypes seem particularly subject to immune modulation and can be effectively regulated by a formal process of ...
A 2-amino acid signature (AK) in the gp120 C1 region was reportedly enriched among the vaccine breakthrough viruses rather than among viruses in unvaccinated monkeys [31]. However, a later study showed that this signature was more likely a mucosal transmission signature and was not enhanced by...