Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression limix_qtlPublic cellsnp-litePublic Efficient genotyping bi-allelic SNPs on single cells vireoPublic Demultiplexing pooled scRNA-seq data with or without genotype reference ...
BANKSY can be switched from cell-type clustering mode to domain segmentation mode by increasing λ, which increases the influence of the neighborhood signature and causes cells to cluster according to tissue domain. We applied BANKSY to multiple datasets across diverse spatial transcriptomic technologies...
f GO enrichment analysis performed on the gene sets associated with neuronal (green), non-neuronal (red), and pancellular (orange) KAT3 peaks. g Volcano plots of RNA-seq analysis for the subset of genes classified as neuronal. Red: upregulated genes; blue: downregulated genes. h BETA ...
Language:All interactivereport/cellxgene_VIP Star135 Enables cellxgene to generate violin, stacked violin, stacked bar, heatmap, volcano, embedding, dot, track, density, 2D density, sankey and dual-gene plot in high-resolution SVG/PNG format. It also performs differential gene expression analysis...
Connect to our innovative, flexible, industry-leading cell and gene therapy products and services that can help accelerate your workflow. All of our solutions are designed with your commercial end-point in mind. Access our Cell & Gene Therapy Product and Service Selection Tool to identify the rig...
Cell composition deconvolution (CCD) is a type of bioinformatic task to estimate the cell fractions from bulk gene expression profiles, such as RNA-seq. Many CCD models were developed to perform linear regression analysis using reference gene expression
The single sample gene set enrichment analysis (ssGSEA) algorithm was used to quantify the relative abundance of each cell infiltration in the TME of BC patients [22]. We obtained the signature gene sets indicating a wide range of human immune cell subtypes from Charoentong’s research, includi...
Moreover, a collection of genome-wide sets of regulatory regions should be provided (BED format). TACO can handle input regulatory region datasets of two kinds: strongly cell-type–specific or weakly cell-type–specific. Each input dataset should be declared as strongly or weakly specific (these...
Gene-Editing Tool Can Improve Efficacy of Adoptive T-cell ImmunotherapyAn abstract is unavailable.Tarapchak
Each cell type can be identified by a uniquely characteristic transcript pattern of gene expressions (i.e., RNA signature) or a uniquely characteristic transcript profile14. However, because the number of clusters depends on the algorithms and parameters, the results are not generally optimized for...