IGHMBP2 - immunoglobulin mu binding protein 2 - Genetics Home ReferenceGenetics Home Reference
immunoglobulin mu-binding protein 2 - chemical and physical properties, structure, melting point, boiling point, density, molecular formula, molecular weight, uses, prices, suppliers, and toxicity/safety/hazards/SDS information.
We have cloned the cDNA encoding the human homologue of S mu bp-2, which binds to single-stranded DNA with 5'-phosphorylated guanine-rich sequences related to the immunoglobulin mu chain switch (S mu) region. The deduced amino acid sequences of the mouse and human S mu bp-2 are 76.5%...
im·mu·no·glob·u·lin (im'yū-nō-glob'yū-lin) One of a class of structurally related proteins. On the basis of the structural and antigenic properties of the H chains, immunoglobulins are classified (in order of relative amounts present in normal human serum) as IgG, IgA, IgM,...
A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin |[mu]| chain gene Of the various classes of antibodies that B lymphocytes can produce, class M (IgM) is the first to be expressed on the membrane of the developing cells. Pr... D Kitamura,J Roes...
im•mu•no•glob•u•lin (ˌɪm yə noʊˈglɒb yə lɪn, ɪˌmyu-) n. 1.any of several classes of globulin proteins that function as antibodies. 2.the fraction of the blood serum containing antibodies. ...
Unprecedented head-to-head conformers of d(GpG) bound to the antitumor active compound tetrakis (mu-carboxylato)dirhodium(II,II). The N7/O6 equatorial binding interactions of the antitumor active complex Rh(2)(OAc)(4)(H(2)O)(2) (OAc(-) = CH(3)CO(2)(-)) with the DNA fragment ...
Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas. heavy chains in nonsecreting pre-B (mu+, L-) cell lines or incompletely assembled Ig precursors in (H+, L+) secreting hybridomas and myelomas. In... ...
2. A polynucleotide encoding a single chain protein that binds to a target receptor, wherein said single chain protein comprises: (a) a binding domain polypeptide capable of binding to said receptor, said binding domain polypeptide being joined to (b) a hinge peptide, said hinge peptide being...
Therefore one site of the RSS (nonamer) functions as high-affinity DNA-binding region that anchors the protein on the DNA, while the other (heptamer) is the site of cleavage. Allelic exclusion and regulation of Ig gene rearrangement. Each B cell expresses only one VH and one VL region ...