Binding immunoglobulin protein (BiP) is a protein marker associated with endoplasmic reticulum (E.R.) stress and is upregulated by metabolic alterations at the tissue level. There is growing proof that changes in the microbiota's makeup that cause infections may have a significant impact on the...
Expression of the Arp Protein, a Member of the M Protein Family, Is Not Sufficient To Inhibit Phagocytosis ofStreptococcus pyogenes Many Streptococcus pyogenes immunoglobulin-binding proteins have structural similarities to the antiphagocytic M protein, including the well-known C repeat... LK Husmann,...
The invention provides an isolated and purified nucleic acid molecule encoding mammalian immunoglobulin A inducing protein (IGIP), and methods of using the IGIP nucleic acid molecule and IGIP, e.g., to prepare antibodies. Also provided is an anti-IGIP antibody and uses therefor.Estes, Mark ...
We have previously characterized a 20 kDa leptospiral surface protein which interacts with C4b-binding protein (C4BP), named Leptospiral complement regulator-acquiring protein A (LcpA). Here we show that LcpA also interacts with human FH, which remains functionally active once......
13. A vaccine according to any of claims 7 to 12, in which the IgA protease is present as part of a fusion protein with the subunit B of the cholera toxin. Claims for the following Contracting State : ES 1. A method for producing an immunoglobulin A1 protease (IgA1 protease) or ...
H Janson,LO Hedén,A Forsgren 摘要: Protein D is an immunoglobulin D-binding membrane protein exposed on the surface of the gram-negative bacterium Haemophilus influenzae. Results reported here indicate that protein D is a lipoprotein. The protein is apparently synthesized as a precursor with an...
The immunoglobulin (Ig)-like domain is a typical feature of proteins belonging to the immunoglobulin superfamily The immunoglobulin (Ig)-like domain is aprotein domainthat is similar inamino acid sequenceand structure to the Ig domains of immunoglobulins (Edelman, 1987; Williams & Barclay, 1988)....
Protein instability is a major obstacle in the production and delivery of monoclonal antibody–based therapies for cancer. This study presents real-time isothermal differential scanning fluorimetry as an emerging method to evaluate the stability of human immunoglobulin G protein with high sensitivity. The...
免疫球蛋白家族(immunoglobulin superfamily) 本家族成员众多,且均与免疫球蛋白有一定的同源性,广泛分布于淋巴细胞、 … www.healthoo.com|基于7个网页 3. 免疫球蛋白超级家族 2.3.2免疫球蛋白超级家族(immunoglobulin superfamily):免疫球蛋白是相隔60～80个氨基酸间有2个半胱氨酸残基S-S结合的11… ...
This protein is a proteolytic cleavage fragment of the receptor involved in the secretion of polymeric IgA onto mucosal surfaces and into bile. Secretory IgA produced locally on mucosal surfaces by plasma cells is thus readily distinguishable from serum IgA. Although not rigorously quantified, the ...