Immunoglobulin-binding proteins include the domain of at least one modified immunoglobulin, the polypeptide of modified immunoglobulin associativity structural domain is by the amino acid sequence of immunoglobulin associativity structural domain and selected from B structure domain, Z structural domains, ...
Binding proteins based on non-immunoglobulin folds In principle, every protein can be converted to a library with a potential binding surface. The diversity of alternative scaffolds that has been developed and still is under development [3] can be brought down to less than a handful of ...
IMMUNOGLOBULIN-BINDING PROTEINS AND RECOMBINANT D 专利名称:IMMUNOGLOBULIN-BINDING PROTEINS AND RECOMBINANT DNA MOLECULES CODING THEREFOR 发明人:GORE, Michael, Graham,POPPLEWELL,Andrew, George,ATKINSON,Anthony,GOWARD, Christopher, Roderick 申请号:GB1991002077 申请日:19911125 公开号:WO92/009633P1 公开日...
An affinity support having improved binding capacity for target proteins. An immunoglobulin-binding protein including a mutant immunoglobulin-binding domai... M Swaroop,M Moussalli,SW Pipe,... 被引量: 0发表: 2018年 Mutated immunoglobulin-binding protein The present invention relates to an immunoglobul...
The structure of the 56-residue B1 immunoglobulin-binding domain from streptococcal protein G has been determined in two different crystal forms. The crystal structures were deduced by molecular replacement, based on the structure of the... T Gallagher,P Alexander,P Bryan,... - 《Biochemistry》 ...
surface display of immunoglobulin A (IgA) and IgE-specific in vitro-selected binding proteins (affibodies) based on Staphylococcus aureus protein A." Appl... E Gunneriusson,P Samuelson,J Ringdahl,... - 《Applied & Environmental Microbiology》 被引量: 76发表: 1999年 Translational regulation of...
by soluble protein A, suggesting that Pmy does not bind to the region between the CH2 and CH3 domains used by many other Fc-binding proteins. 尾... A Loukas,MK Jones,LT King,... - 《Infection & Immunity》 被引量: 220发表: 2001年 NF-HB (BSAP) is a repressor of the murine immun...
purified immunoglobulin (IgE) binding immunogenic proteins, used in test kit for screening patients for allergies to food nutsdoi:US7763709 B2The invention describes an isolated nucleic acid sequence comprising the nucleotide sequence of SEQ ID NO: 1 or a degenerate variant of SEQ ID NO:1. The ...
Other functions of IgA include activation of complement proteins, concurrent with the activation of alternative pathways of this system through the induction of the mannan-bindinglectin[84]. IgA can also bind to and activate multiple receptors such as CD71, known as thetransferrin receptor[85]. Wit...
The present invention relates to modified immunoglobulin-binding proteins, e.g., Staphylococcus protein A, having improved binding specificity for immunoglobulins and methods