Our results demonstrate that the sequential immunization group of animals induced significantly higher IgG endpoint titers against respective HIV Env (autologous) antigen than other control groups. Animals vaccinated sequentially showed an increase in the antibody endpoint titers and IgG antibody secreting ...
2c). Bars represent the means of log transformed titers and the error bars are SEM. P-values are for two-tailed, paired T-test, only statistically significant (p < 0.05) values are shown. (d) Background Strep+ anti-RBD titers in S1pr2- IgkTag/Tag control mice immunized as in Fig....
2). Boosting of DNA-primed animals with a single administration of polyvalent gp120 proteins enhanced antibody titers markedly. The gene gun group had a slightly higher titer than the ID group, especially against three of the four gp120 proteins present in the immunogens (Fig. 2). However, ...
To test this, we captured BG505 SOSIP Env trimers on plates coated with Galanthus nivalis lectin (GNL) (Figure S2C). In GNL ELISA, Env-binding IgGs were observed in all groups. Overall, Env-binding serum titers did not significantly differ between groups, but a trend toward increased ...
Lung virus titers on the X axis are below detection limit. “M2e” in the X-axis means M2e-VLP. Statistical analysis was by two-sided Mann-Whitney U test with correction for ties. Full size image We also determined the H3N2 lung virus load following mock/H3N2 and H1N1v/H3N2 challenge. ...
did not efficiently induce the production of neutralizing antibodies when delivered as a particulate antigen (as part of hepatitis B virus core- like particles), we showed that recombinant JUNV GP1 purified from transfected mammalian cells induced virus-neutralizing antibodies at high titers in rabbits...
Different superscript letters in the same sampling period showed significantly different immunization effects (Duncan's test: p < 0.05). Sa: S. agalactiae group, Ah: A. hydrophila, Biv: bivalent mixed vaccine group. 2.1.2. Antibody Titer of Immunized Broodstock The antibody titer of broodstock ...
The study was designed to detect a 10% decline in antibody titers for children exceeding 2.0 µg/g with 80% power at the 0.05 significance level with data from 140 children. Power calculations were based on prior studies of mercury [26,27] and PCB [1] exposures in children. Baseline ...