358 The high-titer measles vaccine mortality experience highlighted the importance of improving the quality control and evaluating the safety of vaccines used in developing countries.44, 108 Plans to eliminate neonatal tetanus and measles via national immunization days, during which millions of people ...
vectors for CSFV marker vaccine. The high cross-neutralizing titer against CSFV strain Pader was previously observed in anti-Gifhorn sheep sera[90]. But actually T-cell response probably plays an important role in the anti-CSFV immunity induced by BVDV or BDV strains as well. Two chimeric ...
Single dose of protein vaccine with peptide nanofibers as adjuvants elicits long-lasting antibody titer. ACS Biomater. Sci. Eng. 4, 2000–2006 (2018). CAS Google Scholar Li, W. A. et al. The effect of surface modification of mesoporous silica micro-rod scaffold on immune cell activation ...
After 3–7 weeks passed, NAb titer was shown to increase and reached its maiden peak on day 33. However, there was a decline in the NAb titer after 3 months, from 93.3% of patients. Furthermore, a strong positive correlation between NAb titer and levels of plasma proinflammatory cytokines,...
The therapeutic efficacy of whole tumor cell vaccines (TCVs) is modest, which has delayed their translation into personalized immunotherapies in the clinic. Here, we develop a TCV platform based on photothermal nanoparticle-loaded tumor cells, which can
[Generic name] Infectious Bursal Disease Thermo-stable Vaccine, Live (Strain B87). [Trade name] SINVAC IBD.[Active Component & Titer] Live attenuated Infectious Bursal Disease virus (B87 strain), Titer ≥103.5 ELD50/dose.[Pharmaceutical form] Fr...
single dose vaccination of this glycoprotein-loaded nanoparticle was shown to provide a 128-fold higher antigen-specific IgG serum titer compared to that achieved with glycoprotein alone. The glycoprotein-loaded nanoparticle further protected 80% of the immunized mice from Ebola virus challenge, whereas...
Optimally, vaccination should be delayed until the titer of maternal antibody in the young animal has declined to near zero. However, any delay in vaccine administration may leave the animal vulnerable during the resulting “window of susceptibility.” This is potentially life-threatening in crowded,...
The seeded cells were stimulated with the challenge pH1N1, A/Swine/Iowa/A01104104/2017(H1N1) and an H3N2 strain, A/Swine/Iowa/A02135000/2017(H3N2), both at a concentration titer of 5.8 log10 median tissue culture infectious dose (TCID50) per mL. For control purposes, PBMCs were ...
4652Accesses 91Altmetric Metrics Abstract Vaccines have played a central role in combating the COVID-19 pandemic, but newly emerging SARS-CoV-2 variants are increasingly evading first-generation vaccine protection. To address this challenge, we designed “single-cycle infection SARS-CoV-2 viruses” ...