Siglecs are sialic-acid-binding immunoglobulin-like lectins that are mostly expressed by cells of the immune system. Siglecs can be divided into two subsets based on their sequence similarity and evolutionary r
Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in preclinical models and emerging evidence in humans have established the crucial roles of the innate and adaptive immune systems in driving atherosclerosis-associated
This review considers recent advances in our understanding of how C-type lectins in the immune system work, with an emphasis on summarizing the currently available structural information and defining the areas where functional and mechanistic information is still outstanding. Structures of C-type lectins...
Divergent roles for C-type lectins expressed by cells of the innate immune system. Mol Immunol, 2004, 41(11), 1109-21.McGreal, E. P., Martinez-Pomares, L., and Gordon, S. 2004. Divergent roles for C-type lectins expressed by cells of the innate immune system. Mol Immunol 41, ...
P., L. Martinez-Pomares, and S. Gordon. 2004. Divergent roles for C-type lectins expressed by cells of the innate immune system. Mol. Immunol. 41:1109-1121.McGreal, E.P.: Martinez-Pomares L, Gordon S. Divergent roles for C-type lectins expressed by cells of the innate immune ...
(2013). Prophenoloxidase system and its role in shrimp immune responses against major pathogens. Fish Shellfish Immunology, 34, 990–1001. Article CAS PubMed Google Scholar Anselme, C., et al. (2008). Identification of the weevil immune genes and their expression in the bacteriome tissue. ...
Also known as the lymphoid system, is a series of vessels, nodes, tissues, and organs which transport lymp, a clear fluid of filtered plasma, which contains cellular debris, bacteria, and other foreign particles, back into the circulatory system. The lymphatic system is also responsible for ...
Evolution of anaphylatoxins, their diversity and novel roles in innate immunity: insights from the study of fish complement. Vet Immunol Immunopathol 2005; 108:77–89. Article CAS PubMed Google Scholar Ember JA, Hugli TE . Complement factors and their receptors. Immunopharmacology 1997; 38:3–...
This simplistic perception was based on the presence of resident immune cells, the microglia, and barrier systems within the brain, and the assumption that the central nervous system (CNS) lacks lymphatic drainage. This view was revised with the discoveries that higher functions of the CNS, ...
Biomarkers of infection could be assigned to three groups based on their roles as inflammation mediators: molecules expressed on the surface of immune cells, cytokines and acute phase proteins (APPs) [60]. The primary response of the host to infection is known as acute phase reaction (APR), ...