COVID-19Given past experience with widespread viral infections, for example influenza, we expected that SARS-CoV-2 would create a large number of de novo cases of immune thrombocytopenia (ITP). Perhaps a silver lining on the cloud of SARSCoV-2 is that for patients with ITP, the virus is ...
The persistent COVID-19 pandemic since 2020 has brought an enormous public health burden to the global society and is accompanied by various evolution of the virus genome. The consistently emerging SARS-CoV-2 variants harboring critical mutations impact the molecular characteristics of viral proteins a...
Babies Born While Mother Has COVID-19 Could Be Immune to the Coronavirus Babies of women infected with Covid-19 might have a superpower: being born immune to Covid-19. That’s right, according to a paper published in October by the journalEmerging Infectious Disease,babies of female Covid-...
Overall, the study included 38 post-COVID-19 patients three to six months after they left hospital and 29 healthy volunteers (who had no underlying diseases and had not had COVID-19) to compare against. At three to six months, the researchers found that there were more immune cells in th...
Immune response to COVID-19 vaccines in PWH Given the potential for adverse outcomes after SARS-CoV-2 infection, an important consideration is whether optimal immune responses after COVID-19 vaccination are mounted in PWH. There is evidence that some vaccines elicit suboptimal responses in PWH as...
Berger B, Rodgers G (2021) ITP secondary to COVID-19: a comprehensive review of reported cases. Abstract PB0169. Presented at the ISTH; July 17–21, Philadelphia, PA. https://abstracts.isth.org/abstract/itp-secondary-to-covid-19-a-comprehensive-review-of-reported-cases/ Pavord S, Thach...
The COVID-19 pandemic poses a major burden on healthcare and economic systems across the globe. Even though a majority of the population develops only mino
A new study led by the Universities of Sheffield and Oxford with support from the UK Coronavirus Immunology Consortium (UK-CIC) has found that 99 percent of people generate a robust immune response against COVID-19 after just one dose of the Pfizer vacci
Lung immune cells scRNA-seq data: https://covid19.cog.sanger.ac.uk/madissoon19_lung.processed.h5ad. Code availability All codes are available at https://github.com/SoskicLab/aid_sharing. References Bao, Y. K. et al. High prevalence of comorbid autoimmune diseases in adults with type 1...
COVID-19-associated variants had context and cell type-specific eQTL effects, with theIFNAR2variant (rs13050728) in particular having COVID-19-specific and monocytes-specific eQTL effect. In summary, our data linked innate immune cell dysfunction, especially ncMono, with severe COVID-19 and ...