COVID-19 pandemicHUMORAL immunityMEDICAL sciencesThe effectiveness of COVID-19 vaccination is still unclear in individuals with underlying diseases such as HTLV-1 infection. This retrospective cohort study aimed to evaluate the humoral response of COVID-19 vaccines among people living with HTLV-1 (...
But COVID-19, which targets surface cells throughout the respiratory system including in the lungs, has an average incubation of six days and a much slower disease progression. Mathematical modeling suggests that the adaptive immune response may kick in before the target cells are depleted, slowing...
Infliximab, a powerful biologic that is used to treatinflammatory bowel disease(IBD), blunts the body's immune response to COVID-19 infection, indicates research published online in the journalGut. This impaired response may boost susceptibility to recurrent COVID-19 and help drive the evolution o...
Thus, given the key role of the immune system in COVID-19, a deeper understanding of the mechanism behind the immune dysregulation might give us clues for the clinical management of the severe cases and for preventing the transition from mild to severe stages....
The team was hoping to expand their work nationally and internationally to understand why some people die from the COVID-19, and build further knowledge to assist in the rapid response of the disease.
‘The population diversity of HLA molecules, as well as the specificity of their work do not let the virus avoid the T-cell immune response. But the virus has managed to hide its S-protein from one of the HLA molecules. Importantly, most of COVID-19 vaccines (Sputn...
How do we study the immune response? The serum of COVID-19 infected individuals was of interest as it is the part of our blood that contains crucial information about our immune system. Analysis of the serum made it possible to create a detailed timeline of the level of ‘neutralizing antib...
Examining the genomes of patients who have a severe response to COVID-19 will help identify crucial immune-related variants (see 'Investigations into host response to COVID-19'). However, asymptomatic people, the ideal control group for comparison, are extremely difficult to find. Until testing ...
We partnered with Dr. Paula Kavathas of the Yale University School of Medicine, to learn more about how viruses infect people, how the body responds to them, and impact of vaccines on diseases. In our continuing series on COVID-19(Coronavirus), we partne
Obesity may cause a hyperactive immune system response to COVID-19 infection that makes it difficult to fight off the virus, according to a new manuscript published in the Endocrine Society's journal, Endocrinology.