Next, we isolated and enriched the population of CD11b+ cells from the cochlea and immortalized these cells with the 12S E1A gene of adenovirus in a replication-incompetent retroviral vector to derive a novel microglial cell line, designated Mocha (microglia of the cochlea). The resulting Mocha...
永生化人小胶质细胞(SV40转染细胞系)来源于原代人小胶质细胞(纯度99%),并保留了小胶质细胞特异性标记,如Iba1、CD68、TREM2和CD11b。这些细胞适用于研究人类小胶质细胞在健康和疾病中的作用。 Immortalized Human Microglia (SV40 cell line) is derived from Primary Human Microglia Cells (>99% purity) and have...
永生小鼠小胶质细胞来源于原代小鼠小胶质细胞永生化后细胞纯度99%以上,它维持了小胶质细胞特异性标记,如Iba1、CD68、TREM2和CD11b。 Immortalised Mouse Microglia ‐ v-raf/vmyc cell line is derived from Primary Mouse Microglial Cells (>99% purity) and have maintained microglial specific markers such as ...
Cell Morphology :Polygonal Seeding Density:25,000 - 30,000 cells per cm2 Population Doubling Time:28 - 38 hours Reporter: GFP Unit quantity :1x10^6 cells / 1.0 ml Propagation Requirements:The base medium for this cell line is Prigrow III medium available at abm, Cat. No. TM003. To ...
产品名称:Immortalized-Rat-Microglia-SV40 产品型号: 产品展商:ABM 产品文档:无相关文档 简单介绍 Immortalized-Rat-Microglia-SV40 Immortalized-Rat-Microglia-SV40的详细介绍 Print Version BioSafety LevelII OrganismRattus rattus Source OrganRat brain Growth PropertiesAdherent ...
产品名称: Immortalized-Mouse-Microglia-(SIM-A9) 产品型号: 产品展商: ABM产品文档: 无相关文档 简单介绍 Immortalized-Mouse-Microglia-(SIM-A9)Immortalized-Mouse-Microglia-(SIM-A9) 的详细介绍 Print Version BioSafety Level II Organism C57BL/6 mouse Source Organ Postnatal mouse cerebral cortices Growth ...
In addition to the infiltration of peripheral immune cells, neonatal HI induces a strong local inflammatory response, characterized by an increased microglia accumulation and activation [59]. Since dense accumulation of microglia in severely affected HI-injured animals challenges single-cell counting (Supp...
An immortalized human cell line is provided which has the characteristics of human embryonic microglia. Such immortalized microglia cells express CD68, CD11c and MHC class I and II antigens as surface markers; have demonstrable phagocytic properties; and produce progeny continuously while maintained in ...
However, primary microglia culture is time consuming and needs a great number of animals. In our microglia culture, we found a strain of spontaneously immortalized microglia that continued to divide without any known genetic intervention. We confirmed the immortalization of these cells for uninterrupted...
Background Alzheimer's disease is associated with amyloid-beta (Aβ)-induced microglia activation. This pro-inflammatory response promotes neuronal damage, and therapies are sought to limit microglial activation. Screening efforts to develop new pharmacological inhibitors require a robust in vitro cell ...