To improve uptake and cross-presentation of exogenous antigens (Ag) by dendritic cells (DCs), octaarginine-modified liposomes (R8-Lip) were used as a novel strategy for protein-Ag transduction. Immature DCs endocytose macromolecules efficiently. While mature DCs lose their ability to capture Ag, ...
As the most potent professional antigen-presenting cells (APCs), dendritic cells (DCs) bridge the gap between the innate and adoptive immune responses and are the only ones capable of priming naïve T cells1. DCs can be divided into two heterogeneous subsets according to the development stages ...
Mature OSN axons are present throughout the axodendritic domains of glomeruli and can be used to delineate glomerular borders (Fig. 1d). In contrast, the extent to which individual glomeruli are innervated by immature OSN axons varies, and the density of immature OSN axons may be higher proxima...
et al. Implication of scavenger receptors in the interactions between diesel exhaust particles and immature or mature dendritic cells. Part Fibre Toxicol 6, 9 (2009). https://doi.org/10.1186/1743-8977-6-9 Download citation Received14 August 2008 Accepted13 March 2009 Published13 March 2009 DOI...
In this study, immunophenotyping of peripheral blood from COVID-19 patients revealed a significant shift in the ratio between mature and immature neutrophils associating with severity. The increased numbers of immature neutrophils and the disappearance of mature neutrophils likely reflect gradual and sustai...
Overall, a significant increase of immature neutrophil numbers was observed in acute patients as compared to healthy donors or recovered patients, while the number of mature neutrophils decreased (Fig. 1h). CD8 and γδ T-cells are the most affected lymphocyte subsets. To better characterise CO...
then inserted into a retroviral expression vector (a panel of vectors may be used based on their ability to infect mature human CD8+T lymphocytes and to mediate gene expression: the retroviral vector system Kat is one preferred possibility (see Finer et al. (1994) Blood 83, 43). High ...
Injury in the immature brain differs significantly from injury of a mature brain due to numerous developmental, pre-injury, and injury-related factors that can affect recovery while the brain continues to develop. Studies on paediatric injury over a period of 6 to 24 years post-injury showed ...
Injury in the immature brain differs significantly from injury of a mature brain due to numerous developmental, pre-injury, and injury-related factors that can affect recovery while the brain continues to develop. Studies on paediatric injury over a period of 6 to 24 years post-injury showed ...
Expression of Renin-Angiotensin System Genes in Immature and Mature Dendritic Cells Identified Using Human cDNA MicroarrayFIG. 1. Surface phenotype of human iDC and mDC. iDCs were prepared by culturing these monocytes for 5 days in AIM medium containing 10% FCS in the presence of 400 U/ml GM...