During metabolic stress, islet function could be restored by redressing the balance between immature and mature β-cells. Thus, preserving a balance between immature and mature β-cells might be important for islet engineering efforts and more broadly the treatment of type 1 and type 2 diabetes....
Transcriptionally mature and immature β-cells co-exist within the adult islet. How such diversity contributes to insulin release remains poorly understood. Here we show that differences in β-cell maturity, defined using PDX1 and MAFA expression, are required for proper islet operation. Functional ...
Immature , but not Mature , Dendritic Cells are More Often Present in Aggressive Than Chronic Periodontitis : An Immunohistochemical Study... R Motta,C Tirapelli,RJD Silva,... 被引量: 0发表: 2016年 T-cell lymphocytosis associated with lymphocyte-rich thymoma BACKGROUND: Peripheral T-cell lympho...
DCs (dendritic cells) function as sentinels of the immune system. They traffic from the blood to the tissues where, while immature, they capture antigens. They then leave the tissues and move to the draining lymphoid organs where, converted into mature DC, they prime naive T cells. This sug...
Purpose: The purpose of this study is to evaluate migration of technetium-99m hexamethylpropylene amine oxime (-HMPAO) labeled immature and mature dendritic cells (DC) in the mouse. Methods: DC were collected from bone marrow (BM) of tibiae and femurs of mice. Immature and mature DC from ...
Mature or immature glial implants (gliomatosis peritonei) ▸ Small foci of yolk sac tumor ▸ Scattered syncytiotrophoblast cells Immunohistochemistry ▸ GFAP, S-100 and NSE in neuroectodermal elements Differential Diagnosis ▸ Mature cystic teratoma with microscopic foci of immature elements ▸ ...
(n = 5), fetal pig lung without reperfusion; group B (n = 5), fetal pig left lung perfused with human whole blood or serum for 10 minutes; group C (n = 5), fetal pig left lung perfused with human whole blood or serum for 60 minutes; group D (n = 5), mature pig left lung...
Such a method interacting the immature dendritic cells from the animal with an antigen ex vivo so that the immature dendritic cells present the antigen on their surfaces, inducing maturation of the immature dendritic cells ex vivo, and contacting the mature dendritic cells ex vivo with a modulator...
Inhibin‐α Immunohistochemical Expression in Mature and Immature Canine Sertoli and Leydig Cells 来自 NCBI 喜欢 0 阅读量: 20 摘要: Contents Formalin-fixed, paraffin-embedded sections from 32 canine pairs of testes were immunohistochemically examined for Inhibin-α (INHα). Samples were subdivided ...
bone marrow with an increase in immature nucleated red cells which resemble the megaloblasts seen in the bone marrow of patients with pernicious anemia.3... JG Palmer,GE Cartwright,MM Wintrobe - 《American Journal of Medicine》 被引量: 43发表: 1950年 THE TREATMENT OF PERNICIOUS ANEMIA WITH AN...