No cells expressing the proliferative marker Ki67 were observed in the amygdaloid parenchyma, although some of them were found in the vicinity of the lateral ventricle. Immature neurons were also present in the amygdala of squirrel monkeys and cats. These cells also appeared clustered in monkeys, ...
NEUN+ neurons, IBA1+ microglia, S100B+ astrocytes, and OLIG2+ oligodendrocyte lineage cells were observed. d, Sample confocal images showing EdU-incorporated PROX1+ newborn GCs are absent of the astrocyte marker S100B or the more mature neuron marker CALB1 in slice cultures. Asterisks ...
Indeed, we found that around 40% of embryonic cortical neurons at E15.5 were positively labeled by the DSB marker γH2A.X, suggesting a direct link of DNA damage to neuronal apoptosis during cortical development. We also show that up to 30% of γH2A.X-expressing postmitotic immature neurons...
Photoreceptor-specific nuclear receptor (PNR) was used as a postmitotic rod photoreceptor cell-specific marker, glial fibrillary acidic protein (GFAP) as a mature glia cell marker, and microtubule-associated protein (MAP) 2 as a mature neuronal cell marker. Results Nestin was detected in what ...
neurons were undamaged after 30 min of convulsive status epilepticus, but that DNA fragmentation - a marker of apoptotic cell death - was present in both regions after 60 minutes of onset of status epilepticus [75]. Tuunanenet al.examined the extent of damage in ...
Collectively, TRPV1 promoted astrocyte migration thus helped the infiltration of pro-inflammatory cytokines (TNF, IL-1β, IL-6, and iNOS) from astrocytes into the vicinity of neurons to promote epilepsy. Our study provides a strong rationale for astrocytic TRPV1 to be a therapeutic target for...
In this study, the CXCL5 expression in the neurons of the cerebral cortex of the P2 rat pups was higher than that of the P7 and P30 rats. The regional distribution of CXCL5 in the developing cerebral cortex may be related to the proliferation, migration, and differentiation of various cell ...
diameter of C2C12 myotubes. HME treatment demonstrates higher exercise performance and muscle fiber densities than BME treatment. Besides, after KEGG and correlation analyses with biological function after HME and BME treatment, results showed L-Ornithine acts as a “notable marker” after HME treatment...
These neurons were defined as olfactory receptor neuron-1 cells. Under these conditions, a separate class of rarely occurring cells with different morphology demonstrated immunoreactivity to mature markers, such as adenylyl cyclase III and olfactory marker protein. Electrophysiologically, these cells ...
[ 31 ]. there still remains a great need, however, to demonstrate the capability of hucmscs to regenerate matrix bearing the unique qualities, the unique cell morphology, and the expression of molecular phenotype/marker matching that of immature np native tissue. immature np cells originally ...