invasively measured neuralphenotypes, offering a rich framework for evaluating pathophysiological hypotheses and putative mechanisms.Here, we overview some fundamental methods in imaging transcriptomics and outline their application tounderstanding brain disorders of neurodevelopment, adulthood, and neurodegeneration....
Highly sensitive spatial transcriptomics using FISHnCHIPs of multiple co-expressed genes Xinrui Zhou Wan Yi Seow Kok Hao Chen Nature Communications (2024) Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView Takamasa Kudo Ana M. Meireles Eric Lubeck Nature Biote...
Imaging transcriptomics of the brain for schizophrenia û收藏 转发 2 ñ赞 评论 o p 同时转发到我的微博 按热度 按时间 正在加载,请稍候... 查看更多 a 28关注 27粉丝 165微博 微关系 他的关注(28) tongluobing 啊噜哇689 啊庆婚姻中介13829431170 小11you 他...
Compressed sensing for highly efficient imaging transcriptomics_2021_Brian Cleary Lettershttps://doi.org/10.1038/s41587-021-00883-x1 Broad Institute of MIT and Harvard, Cambridge, MA, USA. 2 Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA. 3 Department of Biology, Mass...
A one-stop shop for 3D spatial transcriptomics Tiago Faial Research Highlights15 Jul 2024 Nature Genetics Volume: 56, P: 1327 CRISPRdelight illuminates non-repetitive genomic loci in living cells We demonstrate CRISPRdelight, a robust CRISPR–Cas12a-based method for imaging non-repetitive genom...
Recent advances in imaging-based spatially resolved transcriptomics (im-SRT) technologies now enable high-throughput profiling of targeted genes and their locations in fixed tissues. Normalization of gene expression data is often needed to account for te
Identifying sensitive and specific measures that can quantify myelin are instrumental in characterizing microstructural changes in neurological conditions. Neuroimaging transcriptomics is emerging as a valuable technique in this regard, offering insights into the molecular basis of promising candidates for myelin...
GeoMx DSPSpatial BiologySpatial Molecular ImagingSpatial Transcriptomics Spatial Revolution: An Exciting Future for Cancer Biology Research Many years ago, I was playing hide and seek with my cousins at my grandparent’s house. I was “it” and couldn’t seem to find one of my cousins anywhere...
2024年6月29日,Plant Journal杂志在线发表了哈尔滨师范大学郭长虹教授团队题为Metabolomics and transcriptomics analysis revealed the response mechanism of alfalfa to combined cold and saline-alkali stress的研究论文,揭示了紫花苜蓿对低温和盐碱复合胁迫的响应机制。在本研究中,Lei Liu等人利用多组学分析了两种苜蓿(肇...
Spatial transcriptomics using combinatorial fluorescence spectral and lifetime encoding, imaging and analysis. Nat. Commun. 13, 169 (2022). Article ADS Google Scholar Frei, M. S., Koch, B., Hiblot, J. & Johnsson, K. Live-cell fluorescence lifetime multiplexing using synthetic fluorescent ...