如果需要筛选Cas9成功诱导双链断裂的细胞,推荐用 IL-17D HDR质粒(m) (sc-433663-HDR) 共转染。 关于对照抗体的可用性,请联系技术服务 看到协议线上. 下载 说明书 实验流程 快捷链接 基因信息 种属基因名称基因ID染色质位置亚型(mRNA)即位号码蛋白质即位号码OMIM™ 号码 ...
Lack of IL-17RD did not result in differences in CIA severity, but preliminary data suggest changes in the incidence between IL-17RD knockout mice compared to wild type littermates. Conclusions An inflammatory environment causes synovial fibroblasts to downregulate IL17RD expression. Lack of IL...
Multiple pathways converge to result in the overexpression of T17 cells in the absence of either vitamin D or the vitamin D receptor (VDR). CD4 T cells from VDR knockout (KO) mice have a more activated phenotype than their wild-type (WT) counterparts and readily develop into T17 cells ...
and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.Subunit : Homodimer.Subcellular Location : Secreted.Tissue Specificity : Produced by a variety of cell lines...