IL-22, not simply a Th17 cytokine. Immunol. Rev. 252, 116–132 (2013). Article PubMed CAS Google Scholar Martín, P. et al. CD69 association with Jak3/Stat5 proteins regulates Th17 cell differentiation. Mol. Cell. Biol. 30, 4877–4889 (2010). Article PubMed PubMed Central CAS ...
Recently, interleukin (IL)-23, a cytokine involved in the development of IL-17-producing T helper cells (TH17 cells), was found to have a potential function in the pathogenesis of psoriasis. Here we show that IL-22 is preferentially produced by TH17 cells and mediates the acanthosis induced...
Ouyang IL-22, not simply a Th17 cytokine Immunol. Rev., 252 (1) (2013), pp. 116-132 CrossrefView in ScopusGoogle Scholar [88] I. Rudloff, M. Bachmann, J. Pfeilschifter Mühl H (2012) mechanisms of rapid induction of interleukin-22 in activated T cells and its modulation by ...
Accordingly, TGF-β signaling in CD4+ T cells (specifically Th17 cells) promotes the emergence of IL-22-producing Th17 cells and thereby tumorigenesis in mice. IL-22 single producing T cells, however, are not dependent on TGF-β signaling. We show that TGF-β, via AhR induction, and PI3K...
However, the defect in these mice does not simply involve the scarcity of neutrophils from peripheral tissues such as the colon, but neutrophils are globally absent (including from the circulation, where both CXCR2−/−and CD18−/− mice exhibit neutrophilia [Mei et al., 2012, Scharf...
TREM-1 promotes M1 macrophage polarization in line with increased M1 cytokine profile but not M2 in DSS-treated colonic macrophages. Lamina propria macrophages were isolated from colons of water- or DSS-treated WT and TREM-1 KO mice (n= 6/group) on day 7 post-DSS initiation.aContour plot...
The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur J Immunol. 2009 Dec;39(12):3570-81.The Th17 cytokine IL‐22 induces IL‐20 production in keratinocytes: A novel immunological cascade with potential ...
The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Eur J Immunol. 2009; 39:3570-81. doi: 10.1002/eji.200939687 PMID: 19830738Wolk K, Witte E, Warszawska K, Schulze-Tanzil G, Witte K, Philipp S, et al....
Recently, interleukin (IL)-23, a cytokine involved in the development of IL-17-producing T helper cells (TH17 cells)2,3, was found to have a potential function in the pathogenesis of psoriasis4,5. Here we show that IL-22 is preferentially produced by TH17 cells and mediates the ...
The Th17 cytokine IL-22 induces DMBT1 expression in intestinal epithelial cells dependent on STAT3.Julia DiegelmannDarina CzamaraEmmanuelle Le BrasEva ZimmermannTorsten OlszakAndrea BedynekBurkhard GökeAndre FrankeJürgen GlasStephan Brand