2021年4月13日，清华大学免疫学研究所董晨院士团队在免疫学顶级期刊 Immunity 在线发表了题为：Interleukin-17D regulates group 3 innate lymphoid cell function through its receptor CD93 的研究论文。 该研究首次鉴定了IL-17D的功能性受体为CD93，并揭示IL-17D通过结合CD93调节ILC3细胞的功能并参与维持肠道稳态。
2021 年 4 月 13 日,清华大学医学院董晨院士团队在Immunity上在线发表了题为 Interleukin-17D regulates group 3 innate lymphoid cell function through its receptor CD93 的研究成果 (2)。该研究发现肠上皮细胞来源的 IL-17D 通过与其受体 CD93 结合,在调节三型固有淋巴样细胞(ILC3s)功能并维持肠道稳态中发...
2021年4月13日,国际期刊免疫学(Immunity)在线发表了一篇题为:“Interleukin-17D regulates group 3 innate lymphoid cell function through its receptor CD93”的研究文章。这项来自清华大学董晨院士团队的研究结果发现,来自肠上皮细胞的IL-17D通过与其受体CD93结合,在调节三型固有淋巴样细胞(ILC3)功能和维持肠道稳...
Interleukin-17D regulates group 3 innate lymphoid cell function through its receptor CD93. Huang, Lee, Zhao, Han, Su, Sun, Shao, Ge, Zhao, Bai, He, Wang, Wang, Dong, Immunity(2021 Apr 13) In-Depth Analysis of the Hidradenitis Suppurativa Serum Proteome Identifies Distinct Inflammatory Sub...
Some knowledge of function of IL-17D has been gained by studies using nonmammalian species. In this review, we introduce the structural characteristics, expression patterns, and biological characteristics of IL-17D along with its potential function in the pathogenesis of disease....
………・ 38 中文摘要 白细胞介素17D(IL.17i))在恶性肿瘤进展中作用的研究 擅要目的:恶性肿瘤是一类由于控制细胞增殖机制失常而引起的疾病。根 据世界卫生组织公布的数据显示,2012年全球约有820万人死于恶性肿 瘤,其中中国因恶性肿瘤死亡的人数占全世界的26.9%。目前我国居民恶 性肿瘤的发病率为285.91/10万,...
”37个人简历………・38 中文摘要白细胞介素17D(IL.17i))在恶性肿瘤进展中作用的研究擅要目的:恶性肿瘤是一类由于控制细胞增殖机制失常而引起的疾病。根据世界卫生组织公布的数据显示,2012年全球约有820万人死于恶性肿瘤,其中中国因恶性肿瘤死亡的人数占全世界的26.9%。目前我国居民恶性肿瘤的发病率为285.91 君,已...
Development, cytokine profile and function of human interleukin 17-producing helper T cells[J]. Nat Immunol, 2007,8(9):950-957. [2] Bikle DD. Vitamin D metabolism, mechanism of action, and clinical applications[J]. Chem Biol, 2014,21(3):319-329. [3] Lang PO, Aspinall R. Can we ...
Interleukin 17 (IL-17) has been linked to autoimmune diseases, although its regulation and function have remained unclear. Here we have evaluated in vitro ... - 《Nature Immunology》 被引量: 6741发表: 2005年 Langrish, C.L. et al. IL-23 drives a pathogenic T cell population that induces...
Introduction The proper function of homeostatic mechanisms is essential for protection against unwarranted inflammatory tissue damage1,2. In this regard, developmental endothelial locus 1 (Del-1), an endothelial cell-secreted protein, acts homoeostatically to suppress inflammation in various organs and tis...