价格:元 规格: 10ug 50ug 联系方式:I47-825O-882O立刻购买 买家导航 IL12RB2细胞因子产品基本信息 产品名称: 重组小鼠白细胞介素-12受体亚基β2 产品又名: IL12RB2细胞因子, IL12RB2细胞因子 英文名称: IL12RB2; IL-12 receptor beta 2; IL-12 receptor subunit beta-2; IL-12R subunit beta-2; IL-12...
Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production. IL-12B2 gene acts as tumor suppressor in human acute and chronic B-cell leukemias/lymphomas, IL-12R beta 2 directly restrains ...
下单后预计有货时间 05-May-2025 查看价格 批量或定制请求 抗体检测数据 (1) 已发表图片 (1) Application Created with Sketch. 图:1/2 IL12RB2 Antibody (PA5-21479) in WB Western Blot using IL12RB2 Polyclonal Antibody (Product # PA5-21479). Sample (30 µg whole cell lysate). A: A431. B...
IL12RB2periodontitisSNPsObjectives: The expression of interleukin (IL)-12Rβ2 molecule is a crucial regulatory factor in the T-helper type (Th) 1 differentiation of T cells. To elucidate the role of the cell-mediated immune (CMI) response in the pathogenesis of periodontitis, Japanese periodontal...
and plays a role in Th1 cell differentiation. The up-regulation of IL12RB2 is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense. This subunit is the signaling component...
An ankylosing spondylitis-associated genetic variant in the IL23R-IL12RB2 intergenic region modulates enhancer activity and is associated with increased Th1-cell differentiation 来自 学术范 喜欢 0 阅读量: 7 作者:AR Roberts,M Vecellio,L Chen,A Ridley,A Cortes,JC Knight,P Bowness,CJ Cohen,BP ...
Furthermore, IL-12 driven STAT4 phosphorylation in T cell blasts from healthy individuals was found to correlate with both single allele variants and haplotypes. In conclusion, genetically determined low signaling activity of IL-12R predisposes to the development of LAC.Ignazia Prigione...
It is renowned as a T cell stimulatory factor, fostering T cell proliferation. Furthermore, IL-12 has the capacity to augment the activation of cytotoxic lymphocytes and natural killer cells (NK), thereby enhancing interferon (IFN-纬) production. Empirical evidence consistently demonstrates that IL...
Plasticity within Th cell populations may play a role in enabling site-specific immune responses to infections while limiting tissue destruction. Epigenetic processes are fundamental to such plasticity; however, to date, most investigations have focused on in vitro-generated T cells. In this study, ...
Intriguingly, progress in targeted delivery to the tumor microenvironment renewed high expectations on IL12 as a promising anti-tumor drug either alone or in combination due to its ability to inhibit and/or reprogram immunosuppressive cell subsets. Therefore, to evaluate the efficacy of IL12 and IL...