2. The Role of Chemokine IL-7 in Tumor and Its Potential Antitumor Immunity. J InterferonCytokine Res.2022 Jun;42(6):243-250. 3. Modulation of Signaling Mediated by TSLP and IL-7 in Inflammation, Autoimmune Diseases, and Cancer. Front Immunol.2020 Jul...
Background:IL-7Rsignaling has an important functionin T cell survival byincreasing the expression of antiapoptoticmolecules (Bcl-2 and BclXL) and by maintaining glycolysis andrespiration levels in T cellsthrough activation of multiple signal transduction pathways.背景:IL-7R信号在T细胞存活中起重要作用,...
2. The Role of Chemokine IL-7 in Tumor and Its Potential Antitumor Immunity. J Interferon Cytokine Res.2022 Jun;42(6):243-250. 3. Modulation of Signaling Mediated by TSLP and IL-7 in Inflammation, Autoimmune Diseases, and Cancer. Front Immunol.2020 Jul 21;11:1557...
3. Modulation of Signaling Mediated by TSLP and IL-7 in Inflammation,Autoimmune Diseases, and Cancer. Front Immunol.2020 Jul 21;11:1557
2. The Role of Chemokine IL-7 in Tumor and Its Potential Antitumor Immunity. J InterferonCytokine Res.2022 Jun;42(6):243-250. 3. Modulation of Signaling Mediated by TSLP and IL-7 in Inflammation, Autoimmune Diseases, and Cancer. Front Immunol.2020 Jul 21;11:1557...
J Interferon Cytokine Res.2022 Jun;42(6):243-250. 3. Modulation of Signaling Mediated by TSLP and IL-7 in Inflammation, Autoimmune Diseases, and Cancer. Front Immunol.2020 Jul 21;11:1557 更多生物制药知识尽在微信公众号"小药说药", 欢迎大家关注阅览!
Thus, this study indicates the significance of IL-7Rα signaling in the maintenance of VAT Tregs and glucose homeostasis, revealing a novel role for IL-7 and TSLP in immunometabolism.The Journal of Immunology
Enables cytokine receptor activity. Involved in positive regulation of cell population proliferation and positive regulation of receptor signaling pathway via STAT. Located in cytosol; nucleoplasm; and plasma membrane. Implicated in severe combined immunodeficiency and severe combined immunodeficiency, autosomal...
IL-7R signaling promotes the expansion and survival of developing CD4+ T cells in the thymus [7, 11]. In the periphery, IL-7R signaling supports the survival of naive CD4+ T cells and their differentiation into effector cells [12]. Finally, IL-7/IL-7R signaling is needed for maintenance...
TP53INP1 deficiency maintains murine B lymphopoiesis in aged bonemarrow through redox-controlled IL-7R/STAT5 signaling 研究团队:Bochra Zidi, Christelle Vincent-Fabert, LaurentPouyet, Marion Seillier, Amelle Vandevelde,Prudence N...