白细胞介素-4受体(IL4R)：从基础到应用的前沿探索 白细胞介素-4受体（Interleukin-4 Receptor, IL4R）作为免疫系统中重要的多功能靶点，近年来在生物医药领域引起了广泛关注。IL4R不仅参与调节多种免疫反应，还在肿瘤、过敏性疾病及自身免疫性疾病中发挥关键作用。IL4R主要包含两种类型：I型受体和II型受体。I型...
IL-4受体α(IL-4 receptor α,IL-4Rα)是2型细胞因子IL-4受体与IL-13受体的共享亚基,目前已认为是治疗2型哮喘的重要靶点[7]。此外,胸腺基质淋巴细胞生成素(thymic stromal lymphoprotein,TSLP)、IL-33、IL-25等预警素在多个炎症...
[3]Ul-Haq Z, Naz S, Mesaik MA. Interleukin-4 receptor signaling and its binding mechanism: A therapeutic insight from inhibitors tool box. Cytokine Growth Factor Rev. 2016 Dec;32:3-15. doi: 10.1016/j.cytogfr.2016.04.002. [4] Ho IC, M...
PeproTech多效性细胞因子 IL-4&IL-4 Receptor IL-4是一种多效性的细胞因子,可调节不同的T细胞和B细胞反应,包括细胞增殖、生存和基因表达。由肥大细胞、T细胞和骨髓基质细胞产生,IL-4调节naïve CD4+T细胞分化为Th2细胞,Th2细胞主要分泌IL-4,IL-5,IL - 6、IL-10和IL-13,主要参与体液免疫反应。IL-4的...
Tuning the Cytokine Responses: An Update on Interleukin (IL)-4 and IL-13 Receptor Complexes. Front Immunol. 2018 Jun 7;9:888. doi: 10.3389/fimmu.2018.00888. PMID: 29930549; PMCID: PMC6001902. [10].Orihuela R, McPherson CA, Harry GJ. Microglial M1/M2 polarization and metabolic states. ...
中文名称:白介素4受体(IL4R)重组蛋白英文名称:Recombinant Interleukin 4 Receptor (IL4R) 保存条件:避免反复冻融。2-8°C不超过一个月,-80°C不超过12个月纯度规格:> 95% 产品类别:重组蛋白 白介素4受体(IL4R)重组蛋白 物种Rattus norvegicus (Rat,大鼠)相同的名称,不同的物种,其它种属价格请询价。
4. Qiao, Y., Giannopoulou, E.G., Chan, C.H., Park, S.-H., Gong, S., Chen, J., Hu, X., Elemento, O., and Ivashkiv, L.B. (2013). Synergistic activation of inflamma- tory cytokine genes by interferon-g-induced chromatin remodeling and toll- like receptor signaling. Immunity...
XY-E30068 【中文名称】大鼠促性腺激素释放激素受体抗体(GNRHR-Ab)ELISA试剂盒品牌 【英文名称】Rat anti-gonadotropin-releasing hormone receptor antibody,GNRHR-Ab ELISA试剂盒多少钱 XY-E30069 【中文名称】大鼠血管性血友病因子裂解蛋白酶(ADAMTS13/vWF-cp)ELISA试剂盒品牌 【英文名称】Rat von Willebrand Factor...
HIGH AFFINITY HUMAN ANTIBODIES TO HUMAN IL-4 RECEPTORAn isolated human antibody or antibody fragment thereof which binds to human interleukin-4 receptor alpha (hIL-4R±) with high affinity (K0), capable of blocking hIL-4 and hIL-13 activityジョウエルエイチマーティン...
Tuning the Cytokine Responses: An Update on Interleukin (IL)-4 and IL-13 Receptor Complexes. Frontiers in immunology, 2018. 3. Le Floc'h, A., et al. Dual blockade of IL-4 and IL-13 with dupilumab, an IL-4Rα antibody, is required to broadly inhibit type 2 inflammation. Allergy, ...