Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into ...
mast cells and committed mast cell progenitors.18,22,28–30 The recent development of mice harboring activating mutations of the IL-4 receptor a-chain (IL-4Ra) has provided a very useful new tool for the evaluation of effects of increased IL-4 signaling at the level of the mast cell. We...
Interleukin-4 (IL-4) is a pleiotropic cytokine regulates diverse T and B cell responses including cell proliferation, survival, and gene expression. It has important effects on the growth and differentiation of different immunologically competent cells. Interleukin-4 is produced by mast cells, T cel...
IL-4 modulates the histamine content of mast cells in a mast cell/fibroblast co-culture through a Stat6 signaling pathway in fibroblasts[J] . Yukiko Nabeshima,Takaaki Hiragun,Eishin Morita,Shoji Mihara,Yoshikazu Kameyoshi,Michihiro Hide.FEBS Letters . 2005 (29)...
Il4e12; Interleukin 4; Interleukin 4, isoform 1; Interleukin4; Lymphocyte stimulatory factor 1; Macrophage fusion factor; Mast cell growth factor 2; MCGF2; MFF; MGC79402; Pitrakinra; T cell growth factor 2; TCGF2; IL4_MOUSE; Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1. ...
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized ...
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized ...
protective and pathological responses in gastrointestinal helminth infection MX Ierna1, HE Scales1, KL Saunders1 and CE Lawrence1 Expulsion of the gastrointestinal nematode Trichinella spiralis is associated with Th2 responses and intestinal inflammation, which correlate with a marked mast cell (MC) ...
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation,survival and gene expression.IL-4 is produced by mast cells,T cells,and bone marrow stromal cells.IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2...
Mast cell activation contributes to allergic and other inflammatory diseases—particularly those in which IgG IC may play important roles. Using mouse bone marrow-derived mast cells, we report that IL-4 selectively increases FcγRIII expression without altering FcγRIIb. This enhanced expression ...