Abnormal myelocytic cell development in interleukin-2 (IL-2)-deficient mice: evidence for the involvement of IL-2 in myelopoiesis. Blood. 1998 Apr 15;91(8):2935-47. PMID: 9531604. [3].Gillies SD, Lan Y, Hettmann T, Brunkhorst B, Sun Y, Mueller SO, Lo KM. A low-toxicity IL-2-...
3.https://avengebio.com/ 4.https://news.rice.edu/news/2022/drug-factory-implants-eliminate-mesothelioma-tumors-mice 5.https://baike.baidu.com/item/%E7%BB%86%E8%83%9E%E5%9B%A0%E5%AD%90/658581?fr=aladdin 6.https://baike.baidu.com/item/%E7%99%BD%E7%BB%86%E8%83%9E%E4%BB%8B%E...
IL- 2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation. Am J Physiol 1999; 276: G1461-G1472Schultz M, Tonkonogy SL, Sellon RK, Veltkamp C, Godfrey VL, Kwon J, et al. IL-2-deficient mice raised under germfree conditions develop delayed ...
Foxp3 inhibitory peptide encapsulated in a novel CD25-targeted nanoliposome promotes efficient tumor regression in mice Alejandro Serrano Noelia Casares María J. Garrido Acta Pharmacologica Sinica (2025) CD301b+ dendritic cell-derived IL-2 dictates CD4+ T helper cell differentiation Naoya Tatsumi...
V6A treatment induces less toxicity than s-DAB in mice. Mice were treated daily with PBS, s-DAB, or V6A at indicated doses for 20 d (n = 5). (A) Weights of treated mice. Error bars are mean ± SEM. (B) Survival of treated mice. Statistical analysis by log-rank test. **P <...
naïve T cells express it at lower levels [24]. The trimeric IL-2R is also expressed by endothelial cells, with further CD25 upregulation upon IL-2 treatment [25,26], and signalling can cause the vascular leak syndrome—a known adverse effect of high-dose IL-2 therapy in mice and ...
Mice from most inbred strains are resistant to infection with Leishmania major whereas mice from BALB strains are highly susceptible. Resistance and susceptibility result from the development of Th1 or Th2 cells, respectively. In this report, we document an IL-2 mRNA burst, preceding the reported...
Objective:To study the effects of IL-2Rα mimic peptide(CP) on skin allograft rejection in mice.Methods:Mouse skin allograft model was employed in all groups.The bioactivities were determined by lymphocyte proliferation,one-way MLR,assay of T lymphocyte subset and the level of cytokine in spleni...
The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli. 仅用于科研。不用于诊断过程。未经明确授权不得转售。
[23] Suzuki H, Kundig T M, Furlonger C, et al. Deregulated T cell activation and autoimmunity in mice lacking interleukin 2 receptor β[J]. Science, 1995,268(5216): 1472 -6. [24] Popmihajlov Z, Xu D, Morgan H, et al. Conditional IL 2 gene...