IL-15 AND IL-15R ALPHA SUSHI DOMAIN BASED IMMUNOCYTOKINESMORISSEAU SBASTIEN DANIELTEPPAZ GRALDINEJACQUES YANNICK LAURENT JOSEPHROBERT BRUNO GILBERT MARCDE MARTYNOFF GUY LUC MICHELBECHARD DAVID
linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15R± or derivatives thereof; and uses ...
Appropriate compounds include compounds comprising at least one IL-15Rbeta/gamma binding entity, directly or indirectly linked by covalence to at least one polypeptide which contains the sushi domain of the extracellular region of an IL-15Ralpha....
The present invention relates to a kind of immune cell factors to include (a) conjugate, (2) antibody or its segment, which passes through, to be directly or indirectly covalently attached and the conjugate, the IL-15R 伪 or derivative of sushi structural domain of the conjugate including (...
linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15R卤 or derivatives thereof; and uses ...
linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15R卤 or derivatives thereof; and uses ...
linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15R卤 or derivatives thereof; and uses ...
IL-15RALPHA SUSHI DOMAIN AS SELECTIVE AND POTENT ENHANCER OF IL-15 ACTIVITY THROUGH IL-15RBETA/GAMMA, AND HYPERAGONIST (IL-15RALPHA SUSHI-IL15) FUSION PROTEINPROBLEM TO BE SOLVED: To provide a compound stimulating an IL-15Rβ/γ signalling pathway, and thereby inducing and/or stimulating the...
linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15R伪 or derivatives thereof; and uses ...
Appropriate compounds include compounds comprising at least one IL-15Rbeta/gamma binding entity, directly or indirectly linked by covalence to at least one polypeptide which contains the sushi domain of the extracellular region of an IL-15Ralpha.ジャック,ヤニック...