中文名称: IL10抗体 英文名称: Anti-IL10 Antibody 产品规格: 50μl|100μl|150μl 发货周期: 1～3天 产品价格: 询价 本产品仅可用于科研实验,严禁用于其他非科研用途! 抗体名称Anti-IL10 Antibody 指标别名CSIF,IL 10,IL10,IL-10,IL10A,interleukin 10,TGIF ...
HZ-1145) at 70 ng/well followed by blocking and adding serial diluted IL-10 antibody 69018-1-Ig and 69518-1-Ig respectively. Signal was developed with TMB and stopped by H2SO4. Signal strength was measured by absorbance at 450 nm. This data was developed using the same antibody clone ...
IL-10 (interleukin 10), an anti-inflammatory cytokine, suppresses immune function by blocking the synthesis of proinflammatory cytokines (e.g., IL-1, IL-6, IFN-γ, and TNF-α) in T cells, monocytes, and macrophages, and by inhibiting the expression of cell surface molecules involved in an...
and consequently poor IL-10 blocking. To test this, more prolonged treatment (2 weeks) was made. Figure IB shows that mice treated with atiti-IL-10 on days 0, 2, 4, 6 8. 10 and 12 after the initiation of OVA ingestion had a slight elevation of total antigen-specific antibodies ...
a, Scheme of macrophage conditioning with activated B cells followed by polarization with IL-10 (M-IL-10 and B cells-M-IL-10) and co-culture with CD8+ T cells stimulated with anti-CD3 and anti-CD28 for 72 h in the presence or absence of IL-10 blocking antibodies (Abs). b, c, Re...
The ATG12-ATG5 conjugate also negatively regulates the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Also plays a role in translation or delivery of incoming viral RNA to the translation apparatus. Plays a critical ...
blockade of IL-10R signaling during chronic infection with an IL-10R blocking monoclonal antibody (anti- IL-10R) enhances T-cell recruitment and T cell-derived IFN- , leading to enhanced survival associated with reduced bacterial burdens.151 Furthermore, our group has also recently shown that Mtb...
Interestingly, blocking antibody against IL-10 receptor and inhibition of STAT3 by STAT3 inhibitor S3I-201 attenuates stress-induced lymphocyte apoptosis. Inhibition of IL-10/STAT3 dramatically inhibits stress-induced reduction in IL-12 production. Furthermore, disequilibrium of Th1/Th2 cytokine balance...
and GM-CSF. IL-10 is also known to suppress antigen presentation on antigen presenting cells, enhances B cell survival, proliferation, and antibody production. IL-10 can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. While human IL-10 can ac...
While infusion of IL-10R blocking antibody, initiated at day 60, caused a significant increase in markers of microglial activation and precipitated clinical onset of disease, a targeted overexpression of IL-10 in microglial cells, delivered via viral vectors expressed under CD11b promoter, ...