Exposure to AM-CM resulted in a delayed (> or = 2 h) increase in CBF that was maximal after 24 h exposure (13.70 +/- 0.43 for AM-CM vs. 9.44 +/- 0.24 Hz for medium; P < 0.0001) and which was largely blocked by either anti-TNF-alpha or anti-IL-1 beta antibodies. rTNF-...
1 beta (IL-1 beta), IL-6, and tumor necrosis factor-alpha (TNF alpha) production in humans: high sensitivity of TNF alpha and resistance of IL-6... DeRijk Roel,M David,K Brian,... - 《Journal of Clinical Endocrinology & Metabolism》 被引量: 770发表: 1997年 GM-CSF, IL-1 alpha...
白细胞介素-1B(IL-1B)是促炎细胞因子和急性期反应诱导剂。在微生物诱导后,IL-1B主要由单核细胞,巨噬细胞和树突细胞产生。肿瘤坏死因子-a(TNF-a)由许多不同细胞类型产生,例如 单核细胞,巨噬细胞,T细胞和B细胞。在TNF-a的许多作用中,有针对细菌感染,细胞生长调节,免疫系统调节和参与败血症性休克的保护。产品...
人IL-6 / IL-1beta / GM-CSF / TNF-alpha FluoroSpotPLUS试剂盒又称Human IL-6/IL-1beta/GM-CSF/TNF-alpha FluoroSpotPLUS kit,该产品是Mabtech品牌提供的试剂盒,艾美捷科技作为中国区域代理商提供原装进口产品,并且有独立的产品技术支持人员答疑解惑,售后一直广受老师和学生的好评。为您提供及时的咨询响应,专业...
TNF-α contributes to spinal cord synaptic plasticity and inflammatory pain: Distinct role of TNF receptor subtype 1 and 2 Tumor necrosis factor-alpha (TNF-α) is a key proinflammatory cytokine. It is generally believed that TNF-α exerts its effects primarily via TNF receptor ... Z Ling,T ...
- 1991 - 512 - www.sciencedirect.comdoi:10.1016/1043-4666(91)90424-CChiverton, Stephen G.Hunt, Richard H.Cytokine
During inflammation of the colon, cells of the gut mucosa produce or express numerous inflammatory mediators, such as tumor necrosis factor-(TNF-), interleukin-1(IL-1), and intercellular adhesion molecule 1 (ICAM-1). These mediators have been implicated as contributory factors to the inflammatory...
IL-1 beta, TNF-alpha, and IL-6 have been implicated in the destruction of parotid gland acinar cells (but not duct cells) in autoimmune sialoadenitis. Here we report the temporal alterations of these cytokines in parotid acinar cells that may lead to this specificity in cell death in the...
deletion of the IFNgamma gene had no significative effect on the neurological status of these animals.These results demonstrate that toxic liver injury resulting from exposure to azoxymethane is associated with microglial activation and that selective deletion of TNF-alpha or IL-1beta receptors delays ...
IL-1, IL-6, TNF-and TGF-mRNA expression were same as observed in immunoreactivity for each cytokines. Conclusion: When monocytes are stimulated with LPS under serum-free conditions, IL-6 and TNF-are secreted in early stage of inflammation. In contrast, the secretion of TGF-arise in the ...