研究性的非工程化TIL疗法在ICI耐药的转移性黑色素瘤中显示出了良好的活性,但这种疗法需要系统使用大剂量的IL-2,而IL-2具有明显的高级别毒性,通常需要专业的管理,并且限制了患者的治疗。OBX-115自体工程化TIL疗法不需要与IL-2联用,因...
白介素2(IL-2)博湖ELISA试剂盒大鼠尿激酶(UK)ELISA Kit,48T/96T Test agar fo the residue test acc.to KUNDRAT测试琼脂(残余测试)葡糖杆菌 人表面膜免疫球蛋白D(mIgD)ELISA Kit,48T/96T Agar test PH6.0 for the inhibitor test测试琼脂PH6.0(抑制剂测试)石膏样小孢子菌 人表面膜免疫球蛋白M(mIgM)ELISA...
人补体1抑制物抗体(C1INH)ELISA试剂盒 Human Complement 1 inhibitor autoantibody,C1INH ELISA试剂盒 人B因子(BF)ELISA试剂盒 Human factor B,BF ELISA试剂盒 人类白细胞抗原G(HLA-G)ELISA试剂盒 Human leukocyte antigen G,HLA-G ELISA试剂盒 人补体片断3b(C3b)ELISA试剂盒 Human Complement fragment 3b,...
Interleukin 2 (IL 2) inhibitor in rheumatoid synovial fluid: correlation with prognosis and soluble IL 2 receptor levels. J Clin Immunol. 1990 Mar; 10 (2):115–120.Miossec P, Elhamiani P, Chichehian B, D’Angeac AD, Sany J, Hirn MJ: Interleukin 2 inhibitor in Rheumatoid synovial ...
近日,中国海洋大学/青岛海洋科学技术国家实验室研究人员在知名期刊《Cell Death&Disease》上发表了题为“Discovery of a pyrrole-pyridinimidazole derivative as novel SIRT6 inhibitor for sensitizing pancreatic cancer to gemcitabine”的研究论文,本研究发现了一种新的非竞争性SIRT6抑制剂—8a,并研究了其在胰腺癌的...
4. . HL237 (STAT3 inhibitor) STAT3是IL-21R信号通路的主要下游传感器之一。不过由于IL-21R不仅通过STAT3传递信号,因此HL237在治疗方面可能不如JAK抑制剂有效。此外,STAT3参与了免疫细胞内许多不同的信号通路,这可能导致更多的脱靶效应。 更多自身免疫性疾病文章,点击阅读: ...
FOXP3+ regulatory T cells (Treg) are indispensable for immune homoeostasis and for the prevention of autoimmune diseases. Interleukin-2 (IL-2) signalling is critical in all aspects of Treg biology. Consequences of defective IL-2 signalling are insufficie
B. et al. Discovery of a JAK3-selective inhibitor: functional differentiation of JAK3-selective inhibition over pan-JAK or JAK1-selective inhibition. ACS Chem. Biol. 11, 3442–3451 (2016). Article CAS PubMed Google Scholar Thorarensen, A. et al. Design of a janus kinase 3 (JAK3) ...
:218P1013 Brand:HongTide(上海鸿肽生物) Description:IL-23R inhibitor peptide-1是白介素 23 受体的抑制剂多肽,是由多种非天然氨基酸组成的多肽,其 IC50 值为0.0069 μM。 IL-23R inhibitor peptide-1 is a peptide that inhibits the interleukin 23 receptor and is composed of multiple non natural amino...