Biological process and KEGG analysis revealed that genes in the red module were significantly enriched in cellular response to cytokine stimulus, cell migration, inflammatory response, defense response, and IL-17 signaling pathway (Fig. 3D). For the black module, genes were mainly associated with ...
Through transcriptome sequencing, the differentially expressed genes were found, and the KEGG signal pathway were enriched and analyzed. We found that the differentially expressed genes were involved in a variety of biological processes of the body, especially the regulation of the immune system, ...
KEGG pathway analysis identified that interleukin (IL)‐17 pathway was activated in the regulation of MMP13 in the development of RA. Through observing the alteration of luciferase activity, miR‐19a could indeed bind to the 3′UTR of the downstream of MMP13 , the target association was then ...
清瘟败毒饮对脓毒症大鼠心肌组织IL-17信号通路相关基因表达的影响
B IL-17 signaling pathway is emerged from analysis of enriched KEGG pathways among the respective DEGs in 10 cell clusters. C The mean daily PM2.5 concentration (μg/m3, as shown in left y-axis) and cumulative exposure burden in mouse lungs (μg, as shown in right y-axis) calculated ...
This study found that the IL-17 signaling pathway plays a clue role in multiple pathophysiological processes of HS; SK can prevent and treat HS by inhibiting inflammatory reactions and improving the stress response-ability of body/cell. In this process, it was also found that recombinant IL-17A...
3E-J). We proposed that these signaling pathways may represent potential therapeutic targets for the treatment of AS. Fig. 3 Sex-specific pathways within IL-17-secreting cells. A KEGG pathway enrichment analysis of differentially expressed genes (DEGs) related to signal transduction pathways between...
chemokines in keratinocytes treated with IL-17A by downregulating the expression of IL- 17RA. RNA-seq and KEGG analysis revealed that L-THE significantly regulated the expression of IL-17A and NF-κB signaling pathway-associated genes. Metabolomics ...
KEGG pathway analysis identified that interleukin (IL)-17 pathway was activated in the regulation of MMP13 in the development of RA. Through observing the alteration of luciferase activity, miR-19a could indeed bind to the 3'UTR of the downstream of MMP13, the target association was then ...
(DEFB4A), have known roles in antimicrobial defense56,57. KEGG analysis classified them both into the IL-17 signaling pathway. The association with this pathway was significant (FDR < 0.05). GO analysis classified a selection of the repressed genes into pathways related to cell-cell ...