IL-12A human Fusion Protein 6*His from Proteintech. Produced in E.coli-derived, PET28a, with high quality purity. Cat.No. Ag17625
IL12-Fusion Protein for the Treatment of CancerKey Facts* Fusion protein for the treatment of cancer* Efficacy shown against CD30-positive Hodgkin's lymphoma cells* Activation of immune system thereby reducing side effects knownfrom other medicaments• Dr. A. HombachClinic I of Internal Medicine...
Fusion proteins, such as a bioactive IL-12 polypeptide, which comprise at least two polypeptide monomers (chains of amino acids) joined through a heterologous polypeptide linker and which are bioactive, as well as their production, are described. Also described are tumor cells transduced to express...
,MULLIGAN, RICHARD C. 被引量: 109 摘要: Fusion proteins, such as a bio active IL-12 polypeptide, which comprise at least two polypeptide monomers (chains of amino acids) joined through a heterologous polypeptide linker and which are bioactive, as well as to their production....
Interleukin-12 (IL-12) is an inflammatory cytokine that has demonstrated efficacy for cancer immunotherapy, but systemic administration has detrimental toxicities. Lentiviral transduction eliciting IL-12-producing human sarcoma for autologous reintroduction provides localized delivery for both innate and adaptiv...
Michelle K. Becker-Hapak et al, A fusion protein complex that combines IL12, IL15, and IL18 signaling to induce memory-like NK cells for cancer immunotherapy. Cancer Immunol Res. 2021 September ; 9(9): 1071–1087.
We have professional and advanced research and production capacity for IL-12 p35/IL12A reagents production, including Proteins, Antibodies, cDNA Clones,etc. All IL12A products are produced in house and quality controlled.
Recombinant Human IL-12 stimulates proliferation of PBMC►重组人IL-15蛋白Fig3：Recombinant Human IL-15 stimulates proliferation of CTLL-2►重组人IL-18蛋白Fig4：Recombinant Human IL-18 stimulates proliferation of KG-1►重组人IL-21蛋白Fig5：Recombinant human IL-21 protein stimulates secretion of...
Mirjačić 等探究IL-12和IL-18对转移性黑色素瘤患者NK细胞及其亚群功能和受体特征的影响,IL-12和IL-18体外联合治疗对转移性黑色素瘤患者NK细胞毒性和CD25受体表达可产生良好效果。 图片来源:Mirjačić et al.. J Transl...
C. Bioactive murine and human interleukin-12 fusion proteins which retain antitumor activity in vivo. Nat. Biotechnol. 15, 35–40 (1997). CAS PubMed Google Scholar Tsai, S. J. et al. Exosome-mediated mRNA delivery in vivo is safe and can be used to induce SARS-CoV-2 immunity. J. ...