IL-2 human Fusion Protein 6*His from Proteintech. Produced in E.coli-derived, PET28a, with high quality purity. Cat.No. Ag10199
Validation Data Gallery IL-2 fusion protein Ag24079 SDS-PAGEEnlarge Image¥1080/ 50 μg Cat No. Ag24079 库存:现货 Size 收藏 大规格包装请咨询报价 点击咨询售前客服 点击咨询售后客服 Product Information Peptide Sequence APTSSSTSSSTAEAQQQQQQQQQQQQHLEQLLMDLQELLSRMENYRNLKLPRMLTFKFYLPKQATELKDL...
Further, the present invention is human interleukin-2 and Fc fusion protein recombinant IL-2 receptor binding affinity, so that significantly longer half-life, and has full biological activity of IL-2; IL-2 / Fc significantly enhanced humoral immune response of hepatitis B vaccine stimulated, IL...
同时,信达对于成药性也做了很多摸索,比如对于73-83AA所处loop结构的优化,从而使得IBI363具有更好的成药性,稳定性,表达量和纯度均有很大提高。 罗氏也开发过α-biased IL-2融合蛋白(IL-2Rα-biased IL-2m (T3A, N88D, C125A) IgG1- fusion protein),而主要...
Inability of a Fusion Protein of IL-2 and Diphtheria Toxin (Denileukin Diftitox, DAB389IL-2, ONTAK) to Eliminate Regulatory T Lymphocytes in Patients With MelanomaAttia, Peter; Maker, Ajay V; Haworth, Leah R; Rogers-Freezer, Linda; Rosenberg, Steven A ...
IL-2RG human Fusion Protein 6*His from Proteintech. Produced in E.coli-derived, PET28a, with high quality purity. Cat.No. Ag26397
[4] Lopes JE, Fisher JL, Flick HL, et alALKS 4230: a novel engineered IL-2 fusion protein with an improved cellular selectivity profile for cancer immunotherapyJournal for ImmunoTherapy of Cancer 2020;8:e000673. doi: 10.1136/jitc-2020-000673. ...
ALKS 4230 is an engineered fusion protein comprised of a circularly-permuted IL-2 with the extracellular domain of IL-2Rα, designed to selectively activate effector lymphocytes bearing the intermediate-affinity IL-2R. 展开 关键词: immunotherapy ...
6) EGF-IL-18 fusion protein EGF-IL-18融合蛋白补充资料:融合蛋白 分子式:CAS号:性质:两个不同的蛋白质连成一个大分子。可以通过化学方法连接,也可通过基因的融合来实现。在基因操作中,对一些分子数小的多肽基因常采用融合的方法与某一基因(如lac)相连,二者之间接上某一酶(如凝血酶)的切口,以增加在体内...
To examine the biochemical properties of such a molecule a fusion protein was constructed linking the N-terminus of human IL-2 to the C-terminus of IgG3. A similar fusion between IgGI and IL-2 has previously been shown to bind antigen, generate antibody-dependent cellular cytotoxicity (ADCC)...