Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. It consists of a γ heavy chain in the constant (C) region. The monomeric 150kDa structure of IgG constitutes two identical heavy chains and two identical light chains with molecular weight of...
Nonnative aggregation of an IgG1 antibody in acidic conditions: Part 1. Unfolding, colloidal interactions, and formation of high-molecular-weight aggregates. J Pharm Sci. 2011;100:2087–103.Brummitt RK, Nesta DP, Chang L, Kroetsch AM, Roberts CJ (2011) Nonnative aggregation of an IgG1 ...
IgG1 Fc is a homodimer that is composed of the constant region of the two heavy chains that form the IgG molecule. The Fc fragment mediates opsonization, antibody dependent cellular cytotoxicity (ADCC), and complement activation through the binding to
Mechanism of low molecular weight impurity formation in an IgG1 monoclonal antibody formulation Journal of Pharmaceutical Sciences Volume 114, Issue 2,February 2025, Pages 1464-1471 Purchase options CorporateFor R&D professionals working in corporate organizations. ...
Type Antibody Immunogen Protein Predict reactive species Full Name Heavy chain of Rabbit IgG Observed Molecular Weight 50-55 kDa Gene Symbol Gene ID (NCBI) RRID AB_2881835 Conjugate Unconjugated Form Liquid Purification Method Protein G purification UNIPROT ID N/A Storage Buffer PBS with 0.02%...
mouse IgM, IgG2a, IgG2b, IgG3, and IgA, pooled human sera, and purified human paraproteins. The conjugate has been specifically tested and qualified for Western blot applications. Results with your primary antibody may vary and specificity should be confirmed prior to performing two-color ...
Mechanistic studies involving severe acute respiratory syndrome coronavirus 2 infection and vaccinated individuals reveal that this variant enhances pathogen-specific IgG1+ memory B cell activation and antibody production. This G396R variant may have arisen on a Neanderthal haplotype background. These ...
PE anti-mouse IgG1 Antibody structure CAS No. Chemical Name: PE anti-mouse IgG1 Antibody Synonyms PE anti-mouse IgG1 Antibody CBNumber: CB77428002 Molecular Formula: Molecular Weight: 0 MDL Number: MOL File: Mol file Request For Quotation ...
SPR Data:Human FcRn, His Tag captured on CM5 Chip via anti-his antibody can bind Human IgG1 Fc, No Tag with an affinity constant of 0.28 μM as determined in SPR assay (Biacore T200). 制剂(Formulation) Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose...
PE/Fire 700 Rat IgG1, κ Isotype Ctrl Antibody information, including chemical properties, structure, melting point, boiling point, density, formula, molecular weight, uses, prices, suppliers, SDS and more, available at Chemicalbook.