An epithelial cell surface antigen is described which is defined by monoclonal antibody HEA125 (IgG1). The antibody was raised against the colon carcinoma ... Moldenhauer,Momburg,M?ller,... - 《British Journal of Cancer》 被引量: 225发表: 1987年 Immunoelectrophoretic and immunohistochemical cha...
Characterization of lower molecular weight fragments of recombinant monoclonal IgG1 antibodies using SDS-PAGE and mass spectrometryMajor common degradation patterns of mAbs have been identified as hinge cleavage at ~ AA 220 of HC and N-terminal truncation at ~AA 115 and ~AA 130 of HC. Cleavage...
A major phosphotyrosyl-protein phosphatase from bovine heart is associated with a low-molecular-weight acid phosphatase The phosphotyrosyl [Tyr(P)]-immunoglobulin G (IgG) phosphatase activity in the extracts of bovine heart, bovine brain, human kidney, and rabbit liver can b... J Chernoff,HC ...
Maternal anti-fetal brain IgG autoantibodies and autism spectrum disorder: current knowledge and its implications for potential therapeutics. CNS Drugs. 2015;29(9):715–24. Article PubMed Google Scholar Liao CH, Li HY, Yu HJ, et al. Low serum sex hormone-binding globulin: marker of ...
cyclosporin significantly decreased the antibody titre response. The mouse agglutinating antibody titre was dramatically raised byC. sativusat a dose of 6.25 mg/kg, though. The levels of IgG-1 and IgM antibodies were also elevated by saffron in both primary and secondary immunological reactions [58...
Ahnak, through its N-terminal region, scaffolds the L-type pore-forming α1 subunit and, through its C-terminal region, scaffolds the β subunit of VGCC and the p11/Anxa2 complex. Cell surface expression of the α1 subunits and L-type calcium current are significantly reduced in primary ...
October 1, 2016Liang Zhao, Yan Xiao, Xiao-Liang Wang, Jinjing Pei, Zhi-Zhong Guandonkey anti-goat IgG (SC2020), anti-mouse IgG (SC2005) and Cruz Marker Molecular Weight Standards (SC2035) conjugated with horseradish peroxidase were purchased from Santa Cruz Biotechnology Inc. (USA). OA ...
A low-molecular-weight (LMW) heterofucan (designated fucan B) was obtained from the brown seaweed, Spatoglossum schröederi, and its activity as an inhibitor of capillary-like tube formation by endothelial cells (ECs) was analyzed. Chemical, infrared and electrophoretic analyses confirmed the...
genetic ablation oftspan8in mice resulted in a reduction in the body weight of males fed a normal diet, suggesting that it may have a role in the neural control of metabolism73. This last function might explain the up-regulation observed in the transitional stages in our study, since sex ...
In offspring deficient in FcRn, we expected reduced levels of systemic allergen-specific IgG1, a consequence of decreased absorption of maternal IgG from the lumen of the neonatal gastrointestinal tract. Using this model, we were able to investigate how breast milk IgG affected offspring responses ...