1.2.2 鉴别诊断目前在临床上,有部分肝移植后出现丰富IgG4阳性浆细胞浸润的肝损伤病例被报道。 在同种异体肝移植中,由于富含浆细胞浸润所致肝损伤被称为新发的“自身免疫性”肝炎或浆细胞肝炎(plasma cell hepatitis,PCH),罗碧芬等检索相关PCH的文献发现,PCH...
4.Pusztaszeri M, Triponez F, Pache JC, Bongiovanni M. Riedel's thyroiditis with increased IgG4 plasma cells: evidence for an underlying IgG4-related sclerosing disease?.Thyroid. 2012;22(9):964-968.(Q1 6.6)
它包括弓形虫(Toxplasma，Tox)、风疹病毒(nubellavirus，Rv)、巨细胞病毒(Cytomegalo virus，Cmv)、单纯...
图2 十二指肠溃疡活检组织免疫组化可见多量IgG4阳性浆细胞浸润 Figure 2 Immunohistochemical staining revealed remarkable infiltration of IgG4-positive plasma cells into duodenal tissue 本文是程永静版权所有,未经授权请勿转载。 本文仅供健康科普使用,不能做为诊断、治疗的依据,请谨慎参阅 收藏...
这一类型的形态学特征也与自身免疫性疾病相关的淋巴结肿大有重叠,如类风湿性关节炎、所谓的特发性浆细胞性淋巴增殖性疾病伴多克隆丙种球蛋白血症(idiopathic plasmacytic lymphadenopathy with polyclonal hypergammaglobulinemia;部分病例可能是IgG4相关硬化性淋巴结肿大)。 2. 图2. IgG4相关淋巴结肿大,I型。(A)...
Upon immune activation, B cells must shift rapidly from a metabolically quiescent state to a high energy-consumption state. This metabolic shift is absolutely required for B cells to rapidly undergo clonal expansion, and differentiate into germinal center B cells (GCBCs) and plasma cells that ...
Exosomes originate from the endocytic compartment and are released from cells as multivesicular bodies (MVB) fused with plasma membrane (J Cell Biol 200:373 (2013)).Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center. A range of different functions have...
7、 T-cells & Cytotxic T-cells,15,资料类,In humoral immunity B-cells recognize soluble or cell surface antigens (on extracellular microbes ) and differentiate into antibody secreting plasma cells. In cell-mediated immunity helper T-cells recognize antigens on the surfaces of antigen-presenting ...
4. Saeki T, Saito A, Hiura T, et al: Lymphoplasmacytic infiltration of multiple organs with immunoreactivity for IgG4: IgG4-related systemic disease.Intern Med2006,45:163-167. 5. Kamisawa T, Takuma K, Egawa N, et al: Autoimmune pancreatitis and IgG4-related sclerosing disease.Nat Rev ...
Fibroblast growth factor receptor 1 (FGFR1) is a plasma membrane protein that transmits signals from the extracellular environment, regulating cell homeostasis and function. Dysregulation of FGFR1 leads to the development of human cancers and noncancerous diseases. Numerous tumors overproduce FGFR1, maki...