The aim of the present study was to investigate the effect of low-normal and high-normal levels of IGF-1 in growth hormone (GH) deficient adults on cognition and wellbeing during GH treatment. A randomized, open-label, clinical trial including 32 subjects receiving GH therapy for at least ...
Also disclosed are methods of determining whether a given HIV-infected subject exhibits a normal IGF-1 level, based on a comparison of either the IGF-1 value or the log of the IGF-1 value obtained from a blood-derived sample of the subject with a normative IGF-1 range determined using ...
中国正常成人血清IGF-1的参考范围和其影响因素研究.pdf,学校代码:10023 学号:200801033 中国正常成人血清IGF一1的参考范围 及其影响因素研究 专业年级:北京协和医学院临床医学专业2008级 姓名:徐源 导师:潘慧教授 龚凤英研究员 朱惠娟副教授 北京协和医学院临床学院(
van Bunderen CC, Lips P, Kramer MH, Drent ML. Comparison of low-normal and high-normal IGF-1 target levels during growth hormone replacement therapy: a randomized clinical trial in adult growth hormone deficiency. European Journal of Internal Medicine. 2016;31:88-93....
The free IGF-1 represents the biologically active fraction of IGF-1. We hypothesised that there is a difference in free IGF-1 levels in the urine and serum from patients with TCC and normal subjects. Urine and blood samples were collected from 30 cases of superficial TCC and an equal ...
On normal chow, body weight of male FIGIRKO mice was decreased by 16% at 4 weeks, and this increased to a 42% reduction by 1 year of age (Fig. 1a). Epididymal and inguinal fat pad weights at 4 months were decreased by 24% and 53%, respectively (Fig. 1b). Even more striking ...
increasing list of roles of IGF-I, both in physiological and pathological conditions, underlying that its potential therapeutical options seem to be limited to those proven states of local or systemic IGF-I deficiency as a replacement treatment, rather than increasing its level upper the normal ...
Caution must be undertaken in deciphering the results of a low, normal, or high IGF-I in relation to osteoporosis. Future studies should help define more clearly the possible pathogenic relationship between IGF-I and bone mass. 展开 关键词: Humans Bone and Bones Osteoporosis Insulin-Like Growth...
Serum IGFBP-4 level was normal. Molecular size of IGF-II in the patient’s serum was normal, suggesting normal IGF-II bioavailability. Human osteosarcoma cell proliferation in response to the patient’s serum was similar to sera from age-matched normal controls. Leptin levels were markedly ...
Serum and follicular fluid levels of insulin-like growth factor I (IGF-I), IGF-II, and IGF-binding protein-1 and -3 during the normal menstrual cycle. Insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) have important regulatory functions in ovarian follicular development. ...