Specificity Human IFN-β The VeriKine-HS Human IFN-Beta ELISA Kit is designed to measure low or basal levels of Human IFN-Beta in autoimmune disease sera, healthy serum/plasma, or tissue culture media samples with 1.2 pg/ml LLOQ sensitivity. This assay is suitable for the measurement ...
More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis. 仅用于科研。不用于诊断过程。未经明确授权不得转售。
IFN-beta (Interferon-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis...
产品名称:IFN-beta重组蛋白;IFN-beta protein 纯度: >97% as determined by SDS-PAGE. 内毒素: Less than 1.0 EU/μg as determined by LAL method. 生物活性: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is les...
干扰素-β是一种具有多效性的细胞因子,在类风湿性滑膜组织中表达。 根据体外研究和类风湿guanjie炎(RA)动物模型实验,其作用主要是抗炎。 特别值得关注的是IFN-β减少TNF-α、IL-1β和IL-6的分泌,这些因子都是RA发病的关键因素。同时IFN-β可促进IL-1受体拮抗剂(IL-1Ra)和IL-10等抗炎介质的产生。 每天用干扰...
IFN-beta重组蛋白是一种重要的活性重组蛋白,广泛应用于医院研究、高校、科研单位及生物化工企业。它作为新药开发的关键原料,对推动生物医药发展具有重大意义。店内提供的瑾萱生物IFN-beta重组蛋白,纯度高、内毒素低,支持Human/Mouse/Rat等多种种属,表达宿主多样,且标签可定制。产品储存条件为-80°,保质期长达12个月。
IFN-beta 蛋白, Mouse (HEK293) 是重组的 IFN-β 蛋白,由 HEK293 表达,不带标签。 生物活性:使用感染水泡性口炎病毒 (VSV) 的 L929 细胞进行抗病毒测定,ED50 为3-18 pg/mL。 研究背景:IFN-β 蛋白是一种 I 型干扰素细胞因子,在针对感染、肿瘤和各种炎症刺激的先天免疫反应中发挥着关键作用。其信号传导...
干扰素(IFN)是一种广谱抗病毒剂,并不直接杀伤或抑制病毒,而主要是通过细胞表面受体作用使细胞产生抗病毒蛋白,从而抑制乙肝病毒的复制,其类型分为三类,a-(白细胞)型、 B-(成纤维细胞)型,y-(淋巴细胞)型;同时还可增强自然杀伤细胞(NK细胞)、巨噬细胞和T淋巴细胞的活力,从而起到免疫调节作用,并增强抗病毒能力。
IFN-beta (interferon beta; also fibroblast IFN) is a secreted, monomeric 23-24 kDa member of the alpha/beta interferon family of molecules. It can be produced by almost all cell types in response to bacterial DNA or viral double-stranded RNA and is abundantly secreted by circulating plasmacyto...
Interferon beta is synthesized and secreted by fibroblasts and many other cell types in response to pathogens. IFN-beta binding to type I interferon receptors induces the upregulation of IRF-7 and activation of Rnase L. IRF-7 can exert a positive feedback on IFN-beta production. RNase L clea...