Clinical consequences of defects in the IL-12-dependent interferon- gamma (IFN-gamma) pathway. Clin Exp Immunol 2000; 121:417-25.Lammas DA, Casanova JL, Kumararatne DS. Clinical consequences of defects in the IL-12-dependent interferon-gamma (IFN-g) pathway. Clin Exp Immunol 2000; 121:417...
Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway. IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma. IFN gamma is upregulated ...
JAK/STAT Pathway MDSC-induced Immune Suppression Myeloid-Derived Suppressor Cells Regulatory T Cells Shedding MICA/B Antigens Stat3-mediated Tumor Escape T Follicular Helper Cell Pathway TH1 Pathway (Cellular Immune Response) Th17 Biology TH2 Pathway (Humoral Immune Response) ...
In total, 186 EGFR signaling pathway-related genes were obtained from the Genecards Database. In all the following processes, genes were selected based on statistical significance, namelyp-value less than 0.05. To analyze whether expression, a continuous variable, had an effect on survival, univar...
Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway. IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma. IFN gamma is upregulated ...
Interferon Pathway JAK/STAT Pathway MDSC-induced Immune Suppression Myeloid-Derived Suppressor Cells Regulatory T Cells Shedding MICA/B Antigens Stat3-mediated Tumor Escape T Follicular Helper Cell Pathway TH1 Pathway (Cellular Immune Response) Th17 Biology TH2 Pathway (Humoral Immune Resp...
3458 (Human); 15978 (Mouse); 25712 (Rat); 396991 (Porcine); 281237 (Bovine); 403801 (Canine); 493965 (Feline) Alternate Names IFG; IFI; IFNG; IFNgamma; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma Product Datasheets ...
3458 (Human); 15978 (Mouse); 25712 (Rat); 396991 (Porcine); 281237 (Bovine); 403801 (Canine); 493965 (Feline) Alternate Names IFG; IFI; IFNG; IFNgamma; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma Product Datasheets ...
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy Loss of IFN-gamma pathway genes in tumor cells as a mechanism of resistance to anti-CTLA-4 therapy. Cell 2016;167:397-404... J Gao,L Shi,H Zhao,... - 《Cell》 被引量: 169发表: 20...
This class II cytokine receptor pairs with CDw119 to form the IFN gamma receptor and is an integral part of the IFN gamma signal transduction pathway. CDw119 serves as the IFN gamma binding chain and associates with the IFN gamma beta chain which is required for receptor signaling. The ...