Stockinger S, Reutterer B, Schaljo B, Schellack C, Brunner S, Materna T, Yamamoto M, Akira S, Taniguchi T, Murray PJ, Muller M, Decker T (2004) IFN regulatory factor 3-dependent induction of type I IFNs by intracellular bacteria is mediated by a TLR- and Nod2-independent mechanism....
Distinct roles for IFN regulatory factor (IRF)-3 and IRF-7 in the activation of antitumor properties of human macrophages. Solis, A. Nardin et al., "Distinct roles for IFN regulatory factor (IRF)-3 and IRF-7 in the activation of antitumor properties of human macrophages,... - 《Cancer ...
Chlamydophila pneumoniae infection of the vascular wall as well as activation of the transcription factor IFN regulatory factor (IRF)3 have been linked to development of chronic vascular lesions and atherosclerosis. The innate immune system detects invading pathogens by use of pattern recognition recept...
Given then effects we observed on the different portions of the IFN-β we next investigated the interferon regulatory factor (IRF) family of transcription factors for potential interaction partners with ICP0. It has long been suggested that IRF7, the “master regulator” of IFN-I-dependent immune...
inducible gene I- and TBK1-induced phosphorylation of IFN regulatory factor 3 was significantly diminished when MIP-T3 was overexpressed. Depletion of MIP-T3 facilitated Sendai virus-induced activation of IFN production and attenuated the replication of vesicular stomatitis virus. In addition, MIP-...
(gig2), interferon regulatory factor 1 (irf1), myxovirus (influenza) resistance A (mxa), andviperin(also known as radical S-adenosyl methionine domain containing 2,rsad2)41,42,43,44, in zebrafish embryos with the overexpression of IFN-υ (Fig.2band Supplementary Fig.1a−d). ...
IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts Virus infection, double-stranded RNA, and lipopolysaccharide each induce the expression of genes encoding IFN-α and -β and chemokines, such as RANTES (re... SM Mcwhirter,KA Fitzgerald,J Ro...
IFN Regulatory Factor 8 Represses GM-CSF Expression in T Cells To Affect Myeloid Cell Lineage Differentiation. J Immunol. 2015;194:2369–79.Paschal/A V, Zhang R, 0i C F, et al. IFN regulatory factor 8 represses GM-CSF ... - 《Journal of Immunology Official Journal of the American Asso...
Interferon Regulatory Factor (IRF)-1, originally identified as a transcription factor of the human interferon (IFN)- gene, mediates tumor suppression and m... MJ Armstrong,MT Stang,Y Liu,... - 《Cancer Biology & Therapy》 被引量: 5发表: 2015年 Defective TRAF3 modulates alternative NF-kB ...
Positive feedback regulation of type I IFN genes by the IFN-inducible transcription factor IRF-7. FEBS Lett. 441, 106–110 (1998). Article CAS PubMed Google Scholar Colonna, M. TLR pathways and IFN-regulatory factors: To each its own. Eur. J. Immunol. 37, 306–309 (2007). Article...