3) Chickenβ-actin promoter 鸡β-actin启动子4) β-casein promoter β-酪蛋白启动子 例句>> 5) β-actin gene promoter β-肌动蛋白启动子6) bovine beta-casein promoter 牛β-酪蛋白基因启动子补充资料:IFN-β 分子式:CAS号:性质: 一种抗病毒蛋白质,也称为成纤维细胞干扰素。分子量25 000~30...
Constitutive silencing of IFN-beta promoter is mediated by NRF (NF-kappaB-repressing factor), a nuclear inhibitor of NF-kappaB. EMBO J. (1999). 18:6415-25Nourbakhsh M, Hauser H. Consititutive silencing of INF-beta promoter is mediated by NRF (NF-kappaB-repressing factor), a nuclear ...
Failure to activate the IFN-β promoter by a paramyxovirus lacking an interferon antagonist Failure to activate the IFN-β promoter by a paramyxovirus lacking an interferon antagonist . Virology 415 , 39–46 10.1016/j.virol.2011.03.027 [ Cross... MJ Killip,DF Young,CS Ross,... - 《Virology...
LPS and poly(I:C) stimulation greatly increased IFN-β promoter activity in the presence and absence of PPAR-γ. Without transfection of PPAR-γ expression plasmid, troglitazone treatment alone could not decrease LPS- and poly(I:C)-induced IFN-β promoter activity in RAW264.7 cells (Fig. ...
摘要: Examines the linkage between histone acetylation and chromatin remodeling at the interferon (IFN)-beta promoter in vitro and in vivo. Mechanism of enhanceosome induced PIC assembly; Chromatin remodeling by nucleosome acetylation.年份: 2000 ...
Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and ...
These studies demonstrated that RING finger-deficient ICP0 loses its suppressive action on IFN-β promoter activity when driven TBK1 (Fig. 2B), suggesting a role for ubiquitination dependent regulation of this pathway. In contrast, ICP0-FXE was still able to inhibit TRIF-driven IFN-β promoter ...
DOMAIN-CONTAINING ADAPTERIFN-BETA PROMOTERINDUCIBLE GENE-IREGULATORY FACTOR-3 ACTIVATIONINTERFERON-ALPHA INDUCTIONDEPENDENT PROTEIN-KINASE... E Meylan,J Tschopp - 《Molecular Cell》 被引量: 988发表: 2006年 Apoptosis Induced by the Toll-Like Receptor Adaptor TRIF Is Dependent on Its Receptor Interacting...
Knockdown of endogenous USP17 inhibited virus-, cytoplasmic poly(I:C)- and poly(dA:dT)-induced ac- tivation of the IFN-β promoter and cellular antiviral responses. We further found that knockdown of USP17 inhib- ited RIG-I- and MDA5-induced but not downstream activator-induced activation...
RIG-I and MDA5 are cytosolic sensors of RNAs and interact with a downstream mitochondrial protein, IFN-β promoter stimulator 1 (IPS-1, also called MAVS/VISA/CARDIF), which activates IRF-3 (interferon-regulatory factor 3), NF-κB (nuclear factor-kappaB), and AP-1 (activator protein 1) ...