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Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I–Specific Inhibitory Receptors Regulatory dendritic cells restrain NK cell IFN-gamma production through mechanisms involving NKp46,IL-10,and MHC class I-specific inhibitory receptors...
For an effective CD8+ cytotoxic T cell response to occur during infection, MHC class I molecules must be loaded with antigenic peptides in the endoplasmic reticulum. The cytosolic factor responsible for peptide generation is believed to be the proteasome, with the TAP heterodimer mediating peptide ...
Promotion of NLRC5 by IFN-gamma with upregulation of MHC class I (HLA-ABC) in SKBR3 breast cancer cells, suggesting the contribution to counteracting cancer evasion from immunosurveillance and benefiting cancer immunotherapy.Zhao, Ming-ZhenSun, YuJiang, Xiao-FengLiu, LiSun, Li-Xin...
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