Explain the process of mitosis. Discuss the stages of mitosis. Describe the events that occur in the four phases of mitosis (prophase, metaphase, anaphase and telophase). (a) Describe the primary events that take place at each stage of mitosis and meiosis. (b) Compare mitosis and m...
Bladder tumors are the sixth most common type of tumor [1]. Treatment options vary depending on disease stage and individual differences, such as surgical resection [2], chemotherapy based on different stages [3], neoadjuvant chemotherapy [4], and immunotherapy [5]. The therapeutic effect of ...
Host anti-viral factors are essential for controlling SARS-CoV-2 infection but remain largely unknown due to the biases of previous large-scale studies toward pro-viral host factors. To fill in this knowledge gap, we perform a genome-wide CRISPR dropout
Fig. 1. Diagrammatic representation of the structures of the shoot and root apical meristems. LP: leaf primorium; OC: organising centre; PZ: peripheral zone; PM: primary meristem; QC: quiescent centre; PZ: proliferation zone; SC: central zone. Stem cells within these zones are in a process...
Characterizing the modular structure of cellular network is an important way to identify novel genes for targeted therapeutics. This is made possible by the rising of high-throughput technology. Unfortunately, computational methods to identify functional
of peripheral blood mononuclear cells (PBMCs). We integrated these data to provide a comprehensive view of the COVID-19 multi-omic landscape, enabling us to link transcriptomic and cellular changes with circulating proteins. Supervised learning identified plasma levels of the LRRC15 protein, a ...
Embryonic development of the cerebral cortex: a primer. The development of the cerebral cortex can be divided into several stages (see figure). 1.Patterning: The basic plan of the mammalian brain is laid out at the neural plate stage. At this stage, signaling centers that surround the neural...
Arrest of segregation leads to accumulation of highly intertwined catenated dimers: dissection of the final stages of SV40 DNA replication. When SV40-infected cells are placed into hypertonic medium, newly synthesized DNA accumulates as form C catenated dimers. These molecules consist of two su... ...
Processes implicated in ASDs which occur at later stages of development, such as synaptogenesis and neural circuit formation, may also be modeled using organoids. The accuracy of such models will benefit from continuous improvements to protocols for organoid differentiation. Keywords: Autism spectrum ...
1f), likely reflecting reduction of PARP1 localization and activity after the initial stages of DNA repair. The binding of the biosensor to the microirradiated site was rapid and reversible as shown by FRAP experiments (Supplementary Fig. 1c). To confirm the specificity of this effect, we ...