Discuss the stages of mitosis. Describe the events that occur in the four phases of mitosis (prophase, metaphase, anaphase and telophase). (a) Describe the primary events that take place at each stage of mitosis and meiosis. (b) Compare mitosis and meiosis. What are the phases of ...
To better understand the functional state of NK cells, we used Monocle 2 to determine their developmental trajectory. Pseudo-time analysis showed that NK cells were divided into different stages on the time trajectory (Fig. 6C), that is, different functional states. ResponseScore grouping can ...
Embryonic development of the cerebral cortex: a primer. The development of the cerebral cortex can be divided into several stages (see figure). 1.Patterning: The basic plan of the mammalian brain is laid out at the neural plate stage. At this stage, signaling centers that surround the neural...
Host anti-viral factors are essential for controlling SARS-CoV-2 infection but remain largely unknown due to the biases of previous large-scale studies toward pro-viral host factors. To fill in this knowledge gap, we perform a genome-wide CRISPR dropout
Processes implicated in ASDs which occur at later stages of development, such as synaptogenesis and neural circuit formation, may also be modeled using organoids. The accuracy of such models will benefit from continuous improvements to protocols for organoid differentiation. Keywords: Autism spectrum ...
Arrest of segregation leads to accumulation of highly intertwined catenated dimers: dissection of the final stages of SV40 DNA replication. When SV40-infected cells are placed into hypertonic medium, newly synthesized DNA accumulates as form C catenated dimers. These molecules consist of two su... ...
‘Golgi-cisternae peri-centriolar stack re-organisation’. Both are likely to reflect the extensive cell division of immunocytes that occurs in COVID-19. For instance, the pericentriolar stacks of Golgi cisternae undergo extensive fragmentation and reorganization in mitosis. Similarly, polo-like ...
This finding suggests that superoxide accumulation causes problems only in certain tissues and only at defined stages of animal development [30]. The importance of superoxide accumulation in developing root tips may reside in its effects on intracellular pH rather than its reactivity per se. A ...
123 422 Hum Genet (2010) 128:421–431 Several studies indicate that the expression profile of genes residing within the AZFc/AZFb regions is specific to and essential for individual developmental stages of human spermatogenesis (Kleiman et al. 2007; Lardone et al. 2007; Shinka et al. 2004; ...
1f), likely reflecting reduction of PARP1 localization and activity after the initial stages of DNA repair. The binding of the biosensor to the microirradiated site was rapid and reversible as shown by FRAP experiments (Supplementary Fig. 1c). To confirm the specificity of this effect, we ...