Acute myocardial infarction (AMI) has two clinical characteristics: high missed diagnosis and dysfunction of leukocytes. Transcriptional RNA on leukocytes is closely related to the course evolution of AMI patients. We hypothesized that transcriptional RN
Minichromosome Maintenance Complex Component 4 (MCM4) is a vital component of the mini-chromosome maintenance complex family, crucial for initiating the replication of eukaryotic genomes. Recently, there has been a growing interest in investigating the s
we can see that the resulting k-NN models generally had a high accuracy when trained at the batch (80%) and cumulative (90%) levels for both the T11 and T12 cell models, suggesting that the assay is robust with well-resolved controls and there are no major batch effects present (Supplem...
However, the heterogeneity of breast cancer cell metabolism, even within classifications, suggests a necessity for an individualised approach to treatment in breast cancer patients. Methods: The metabolic phenotypes of a diverse panel of human breast cancer cell lines representing the major breast cancer...
Fetal urine is a major contributor of amniotic fluid and both amnion cells and amniotic fluid WBC secrete their metabolites into the amniotic cavity. Never- theless, a possible explanation for the shift from carbohy- drate-rich to amino-acid-predominant metabolites could be a fetal catabolic ...
Consequently, we investigated the correlation between county-wise drought severity and the yield of a few major crops in Senegal. County-wise crop yield survey data for Senegal from 2009 to 2019 were collected from the National Agency for Statistics and Demography (ANSD), an official service for...
“the conditions in which people are born, grow, live, work, and age…shaped by the distribution of money, power, and resources at global, national, and local levels”4. SDoH may be adverse or protective, impacting health outcomes at multiple levels as they likely play a major role in ...
Secoiridoids are the major bioactive compounds in S. mussotii. To better understand the secoiridoid biosynthesis pathway, we generated transcriptome sequences from the root, leaf, stem, and flower tissues, and performed de novo sequence assembly, yielding 98,613 unique transcripts with an N50 of ...
Infants were randomized to Epo treatment or placebo within 24 h of birth, with study drug continued until 32–6/7 weeks corrected age. Infants with major life-threatening or chromosomal anomalies hematopoietic crises such as DIC or hemolysis, polycythemia, congenital infection or prior use of Epo...
(ML) analysis. To do so, we combined the predictions from two independent random forest classifications, based on only-expression or only-methylation data. Using two independent models allowed the inclusion of samples for which only one of these data sets was available, thus maximising the power...