In miscellaneous TCGA cancers, the correlation between MCM4 expression and molecular and immunological subtypes was found to be significant. The expression of MCM4 has been found to be associated with molecular subtypes in eleven different types of cancer and 14 types of immune classifications. These...
During drug development, it is essential to gather information about the change of clinical exposure of a drug (object) due to the pharmacokinetic (PK) drug-drug interactions (DDIs) with another drug (precipitant). While many natural language processing (NLP) methods for DDI have been published...
2,3. However, our ability to address these disparities remains limited due to an insufficient understanding of their contributing factors. Social determinants of health (SDoH), are defined by the World Health Organization as “the conditions in which people are born, grow, live, work, and age…...
8 However, the prescribing of appropriate polypharmacy in the elderly remains a complex issue and much work has been undertaken to classify specific drug classes or individual drugs which may be particularly problematic in the elderly. 8 These lists of drug classifications encourage more appropriate ...
With its numerous classifications,trying to identify and treat pain can be an intimidating and disheartening task. Accepting the concept that pain is simply our body trying to communicate with us is difficult, especially when it is occurring. As frustrating as it can be, oftentimes the first step...
Variant classifications, databases and genotype-phenotype correlations. Arch. Pediatr. 2020, 27, eS13–eS18. [Google Scholar] [CrossRef] Sosnay, P.R.; Salinas, D.B.; White, T.B.; Ren, C.L.; Farrell, P.M.; Raraigh, K.S.; Girodon, E.; Castellani, C. Applying Cystic Fibrosis...
Cancer cells can multiply when there is estrogen in the bloodstream since the majority of breast cancers include estrogen hormone receptors (ERs) [3]. Patients with BC benefit from medications that prevent DNA damage, decrease cell cycle progression and division, or trigger apoptosis. Additionally, ...
dissociative disorders, and hundreds more. It also clarifies common terminology, such as autism spectrum and gender dysphoria, to create clarity across the many branches of psychology. However, the DSM is not the only diagnostic tool available, and many therapists treat symptoms individually. If you...
Effective therapies exist for osteoporosis, but how should those who require therapy be identified? In this chapter we present the rationale behind identifying those at risk through considering past medical history of previous fractures, use of dual X-ra
For emotion classifications, eight emotions have been considered, as proposed by Clynes [49]. These emotions and profile information used for their examination has been described in Table 5. Int. J. Environ. Res. Public Health 2018, 15, 2907 12 of 24 The emotional states have been identified...