Simulated percentage points for the null distribution of the likelihood ratio test for a mixture of 2 normals Biometrics, 44 (4) (1988), pp. 1195-1201 Google Scholar [59] G.J. Mclachlan On bootstrapping the likelihood ratio test statistic for the number of components in a normal mixture ...
These data demonstrate that CD166high WSU-HN13 cells have CSC features and suggest that CD166 is a novel marker for stem-cell-like components of HNSCC. Moreover, considering the high rate (>90%) of CD44+ cells in the CAL27 and WSU-HN13 populations, we did not try to investigate the...
The results showed no clear differences in any of the components (Additional file 1: Figure S8). To test for possible confounding effects within T cell subsets, we performed deconvolution analysis of expression profiles from the CD4+ T cells using profiles from Th1, Th2, Th17, and Treg cells...
We recruited two cohorts of ESKD patients on haemodialysis presenting with COVID-19 (Fig.1a). The Wave 1 cohort consisted of 53 patients recruited during the initial phase of the COVID-19 pandemic (April-May 2020) (Supplementary Table1). Serial blood sampling was carried out where feasible (...
Ordinary Differential Equations (ODEs) describing the tumor, key components of the immune system, and seven treatments. Numerous combination therapies were evaluated considering both the degree of tumor inhibition and the predicted synergistic effects, integrated into a decision tree. Our simulations ...
The term “inactivated tumor suppressor gene” refers to p53 and mutants thereof p16, p120, BRCA1, BRCA2, components of the notch signaling pathway, components of the hedgehog signaling pathway and components of the wnt signaling pathway. The phrase “extra cellular matrix (ECM)” refers to the...
[24]. Additionally, by demonstrating that a CNN can dynamically detect the different components that we observe via 2D transperineal ultrasound of the pelvic floor, we will be able to study different pathologies, such as pelvic organ prolapse. Until recently, ultrasound was used to diagnose ...
Understanding genotype-by-environment interactions (G × E) is crucial to understand environmental adaptation in mammals and improve the sustainability of agricultural production. Here, we present an extensive study investigating the interaction of
The identification of host cell factors for virus entry is useful for the molecular explanation of viral tropisms and often leads to a more profound understanding of virus-induced diseases. Severe fever with thrombocytopenia syndrome (SFTS) is an emergin
In the last years, microarrays, sequencing, and mass spectrometry have been used for global identification of the secretome components13,16,17,20. The development of several bioinformatic tools allow the prediction of secreted proteins based on genomic/transcriptomic annotations and in the interpretation...