These metabolic products can modulate renal, pulmonary, and cardiovascular functions, vascular tone, and inflammatory responses as paracrine factors and second messengers [91–93]. The COX pathway has two main enzymes, COX-1 and COX-2, which are critical in the regulation of inflammation and ...
Inflammatory damage induced by metabolic upheaval also leads to a number of corollary pathologies that derive from diabetes (e.g., nephropathy, cardiomyopathy and retinopathy), where the ECS has been shown to play a role, as suggested by the fact that podocytes and proximal tubular cells over-...
FATP and FABP are closely linked to metabolic inflammatory process through their ability to supply FA to critical lipid metabolic pathways for TG, PL synthesis, FA oxidation, and recently as transporter of key LCFA to the nuclear receptor (NR) to modulate both metabolic and inflammatory ...
9 RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook eicosanoid (redirected fromIcosanoid) Medical Encyclopedia Related to Icosanoid:prostaglandin ei·co·sa·noid (ī′kō-sə-noid′) n. Any of a group of substances that are derived from arachidonic acid, ...