The Notch pathway is active in a broad spectrum of human cancers, including breast, colorectal, lung, prostate, glioblastoma, and pancreatic cancer6. Notch signaling is positively associated with pancreatic tumor initiation, progression, and drug resistance in both cell lines and genetic mutant mouse...
Diagnoses of Gliosarcoma and Giant Cell Glioblastoma were excluded from the present study. Inclusion criteria required cases to have been actively followed up, not previously diagnosed with a primary cancer, and to have pathologic confirmation of the GB diagnosis. From the 32,531 GBs that met the...
The biological response of glioblastoma cells to NDV infection has recently been recognized as necroptosis [89]. TNF members, TLRs, and DNA and RNA sensors can all trigger necroptosis, which is a type of programmed cell death that is not dependent on caspase 8. The receptor-interacting protein ...